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Article
Enhanced frequency of a PTPRC (CD45) exon A mutation (77C→G) in systemic sclerosis
A point mutation in exon A (C to G transversion at position 77) of human PTPRC (CD45) has recently been associated with the development of multiple sclerosis (MS) for at least a subgroup of patients. In the pr...
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Chapter
Microchimerism in Organ Transplantation
Following an allogeneic or xenogeneic organ transplantation, donor-type cells or genetic material can be detected in blood and in peripheral organs or tissues of experimental animals. This phenomenon was first...
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Chapter and Conference Paper
Paternity Testing by Oligonucleotide DNA Fingerprinting: A Multi-Center Study Proving Reliability and Validity
While Jeffreys and co-workers (1) demonstrated in an extensive study of 1702 paternity cases that paternity testing with multi-locus (ML) probes 33.6 and 33.15 is effective and reliable, this technique neverth...
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Chapter
Oligonucleotide DNA fingerprinting: Results of a multi-center study on reliability and validity
We report the results of an empirical study of 256 paternity cases referred to 7 different German laboratories for DNA fingerprinting with oligonucleotide probe (CAC)5/(GTG)5. All parameters characteristic of suc...
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Article
On the potential of simple repetitive DNA for fingerprinting in clinical, forensic, and evolutionary dynamic studies
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Article
Characterization of hypervariable locus-specific probes derived from a (CAC)5/(GTG)5 multilocus fingerprint in various Eurasian populations
Population genetic studies were performed using oligonucleotide probes (Hz1103, Hz4103, and Hz4201) that recognize three hypervariable loci (D11S859, D9S128 and D22S265) in the human genome. DNA from 17 Eurasi...
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Article
DNA Fingerprinting with the oligonucleotide probe (CAC)5/(GTG)5: somatic stability and germline mutations
DNA fingerprints were generated from various human somatic tissues and from peripheral blood of 179 children and their 80 parents using (CAC)5/(GTG)5 oligonucleotide probes. Whereas somatic stability of the finge...
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Article
The spectrum of β-thalassemia mutations in northern and northeastern Thailand
A total of 123 β-thalassemia genes from northern (n = 113) and northeastern (n = 10) Thailand were examined. Using five oligonucleotide probes, the mutation in 108 genes (88%) was identified: 50 nonsense 17, 49 f...
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Article
DNA haplotypes and frameworks linked to the β-globin locus in an Austro-Asiatic population with a high prevalence of hemoglobin E
DNA haplotypes (HT) and frameworks (FW) linked to the β-globin locus were determined by restriction fragment analysis using eight restriction enzymes on chromosomes bearing the HbA gene (HBB*A) or the HbE gene (H...
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Article
β-Globin gene linked DNA haplotypes and frameworks in three South-East Asian populations
DNA haplotypes and frameworks (numbers in parenthesis) linked to the β-globin gene were determined by restriction fragment analysis using eight restriction endonucleases on 86 (97) chromosomes bearing the norm...
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Article
Segregation of cystic fibrosis allele
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Article
Linkage relationships and allelic associations of the cystic fibrosis locus and four marker loci
The linkage relationships between the cystic fibrosis (CF) locus and four marker loci (MET-H, MET-D, D7S8 and D7S16), allelic associations between these loci and the extent of informativity at these marker loc...
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Chapter and Conference Paper
Control of Gene Expression During the Early Phase of Chloroplast Development
Light induces changes in the expression of nuclear and chloroplast genes in higher plants [3, 4, 10, 27] and algae 13]. These alterations belong to the most impressive examples in the regulation of genes both ...
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Chapter and Conference Paper
Blue Light Effects in Cell Cultures
Greening is a complex process which is controlled by light on various levels. Generally, the photoreceptor systems involved respond to both blue and red light. In cell cultures of tobacco (Nicotiana tabacum var.S...