16 Result(s)

Article

Construction of Mono-, Bi- and Trinuclear Clusters to Modify Wells–Dawson Anions through Using Different Transition Metals and Flexible Bis(Pyrazole) Ligands

Three new Wells–Dawson compounds, namely [Co^II(edpz)(H₂bdpm)₃][(H₄P₂W₁₈O₆₂)] (1), [Cd^II₂(mpz)(H₂bhpe)_2.5(H₂O)(H₂P₂W₁₈O₆₂)] · (ppz) · 6H₂O (2) and [Cu^II₃(ppz)(H₂bhpe)₂(P₂W₁₈O₆₂)(H₂O)₃] · 2H₂O (3) (edpz = 4-ethyl-3...

A. X. Tian, Y. B. Fu, H. P. Ni, J. N. Liu… in Russian Journal of Inorganic Chemistry (2020)

Article

Hypermethylation of BRCA1 gene: implication for prognostic biomarker and therapeutic target in sporadic primary triple-negative breast cancer

Paraffin sections from 239 cases of surgical resected mammary gland carcinomas were assessed to determine the role of BRCA1 gene methylation in sporadic triple-negative breast cancer and to evaluate the relations...

X. Zhu, L. Shan, F. Wang, J. Wang, F. Wang, G. Shen… in Breast Cancer Research and Treatment (2015)

Article

Influence of phase and morphology on thermal conductivity of alumina particle/silicone rubber composites

Silicone rubber filled with thermally conductive alumina is fabricated as a class of thermal interface materials in this work. The thermal conductivity of the prepared alumina/silicone rubber composite is meas...

J. P. Cheng, T. Liu, J. Zhang, B. B. Wang, J. Ying, F. Liu… in Applied Physics A (2014)

Article

A novel 3p22.3 gene CMTM7 represses oncogenic EGFR signaling and inhibits cancer cell growth

Deletion of 3p12-22 is frequent in multiple cancer types, indicating the presence of critical tumor-suppressor genes (TSGs) at this region. We studied a novel candidate TSG, CMTM7, located at the 3p22.3 CMTM-gene...

H Li, J Li, Y Su, Y Fan, X Guo, L Li, X Su, R Rong, J Ying, X Mo, K Liu… in Oncogene (2014)

Article

Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients

Using genome-wide methylation screening, we identified that paired box gene 5 (PAX5) is involved in human cancer development. However, the function of PAX5 in gastric cancer (GC) development is largely unclear. W...

X Li, K F Cheung, X Ma, L Tian, J Zhao, M Y Y Go, B Shen, A S L Cheng, J Ying… in Oncogene (2012)

Article

Epigenetic disruption of interferon-γ response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas

16q24 is frequently deleted in multiple tumors including cancers of nasopharynx, esophagus, breast, prostate and liver. By array comparative genomic hybridization (aCGH), we refined a 16q24 hemizygous deletion...

K Y Lee, H Geng, K M Ng, J Yu, A van Hasselt, Y Cao, Y-X Zeng, A H Y Wong… in Oncogene (2008)

Article

Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas

Tumor suppressor genes (TSGs) often locate at chromosomal regions with frequent deletions in tumors. Loss of 16q23 occurs frequently in multiple tumors, indicating the presence of critical TSGs at this locus, ...

H **, X Wang, J Ying, A H Y Wong, H Li, K Y Lee, G Srivastava, A T C Chan… in Oncogene (2007)

Article

Identification of a novel tumor transforming gene GAEC1 at 7q22 which encodes a nuclear protein and is frequently amplified and overexpressed in esophageal squamous cell carcinoma

By comparative DNA fingerprinting, we identified a 357-bp DNA fragment frequently amplified in esophageal squamous cell carcinomas (ESCC). This fragment overlaps with an expressed sequence tag mapped to 7q22. ...

F B F Law, Y W Chen, K Y Wong, J Ying, Q Tao, C Langford, P Y Lee, S Law… in Oncogene (2007)

Article

Epigenetic disruption of two proapoptotic genes MAPK10/JNK3 and PTPN13/FAP-1 in multiple lymphomas and carcinomas through hypermethylation of a common bidirectional promoter

J Ying, H Li, Y Cui, A H Y Wong, C Langford, Q Tao in Leukemia (2006)

Article

Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation

Protocadherins constitute the largest subgroup in the cadherin superfamily of cell adhesion molecules. Their major functions are poorly understood, although some are implicated in nervous system development. A...

J Ying, H Li, T J Seng, C Langford, G Srivastava, S W Tsao, T Putti, P Murray… in Oncogene (2006)