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Article
Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention
Tobacco products present a deadly combination of nicotine addiction and carcinogen exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless tobacco products lead to unaccepta...
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Article
Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers
It is unclear why Black smokers in the United States have elevated risk of some tobacco-related diseases compared to White smokers. One possible causal mechanism is differential intake of tobacco toxicants, bu...
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Article
Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program
The Environmental Influences on Child Health Outcomes (ECHO) Program will evaluate environmental factors affecting children’s health (perinatal, neurodevelopmental, obesity, respiratory, and positive health ou...
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Article
Open AccessTobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers
The Multiethnic Cohort Study has demonstrated that African Americans and Native Hawaiians have a higher risk for lung cancer due to cigarette smoking than Whites while Latinos and Japanese Americans have a low...
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Reference Work Entry In depth
Tobacco Carcinogenesis
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Living Reference Work Entry In depth
Tobacco Carcinogenesis
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Protocol
Quantitation of Acetaldehyde-DNA Adducts: Biomarkers of Alcohol Consumption
DNA adduct measurements provide valuable information about DNA damage associated with exposure to specific genotoxicants. N 2-Ethylidene-dGuo, the major DNA adduct formed upon reaction of acetaldehy...
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Protocol
An Approach to the Evaluation of Berries for Cancer Prevention with Emphasis on Esophageal Cancer
Our laboratory has f cancer prevention using freeze-dried berries, mainly black raspberries, for more than two decades. Berries contain many known agents with chemopreventive potential including certain vitami...
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Chapter
Anthocyanins and Cancer Prevention
Anthocyanins are members of a class of flavonoid compounds commonly known as plant polyphenols. They are responsible for the blue, purple, red and intermediate colors of many flowers, leaves, vegetables and fr...
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Article
Perspective: Tackling the real issues
Successful prevention requires attacking the causes, says Stephen S. Hecht—and the main target remains tobacco.
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Reference Work Entry In depth
Tobacco Carcinogenesis
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Chapter
Tobacco Smoke Carcinogens and Lung Cancer
Cigarette smoking is the major cause of lung cancer, the largest cancer killer in the world. This chapter discusses the role of cigarette smoke carcinogens as causes of lung cancer. A general mechanistic frame...
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Article
Chemoprevention of lung carcinogenesis in addicted smokers and ex-smokers
Lung cancer kills more than 3,000 people every day, and most of this toll is due to cigarette smoking. Although tobacco control is clearly the most desirable w...
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Reference Work Entry In depth
Tobacco Carcinogenesis
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Chapter
Human Phenanthrene Metabolites as Probes for the Metabolic Activation and Detoxification of Carcinogenic Polycyclic Aromatic Hydrocarbons
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Article
Cigarette smoking: cancer risks, carcinogens, and mechanisms
Cigarette smoking causes about 30% of all cancer mortality in developed countries. Although smoking is decreasing in developed countries, it is increasing in some develo** countries.
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Article
Re: Foulds and Ramstrom: Cancer Causes and Control 17: 227–228 (2006) and Henley et al., Cancer Causes and Control 16: 347–358 (2005). How Smokeless Tobacco can Cause Lung Cancer
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Article
Correction: Tobacco carcinogens, their biomarkers and tobacco-induced cancer
Nature Reviews Cancer 3, 733–744 (2003) There is an article (October 2002) associated with this correction. Please click here to view it. On page 740 of this article, it was inadvertently implied that the auth...
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Article
Tobacco carcinogens, their biomarkers and tobacco-induced cancer
Tobacco products cause a variety of cancers, including those of the lung, oral cavity, nasal cavity, larynx, oropharynx, hypopharynx, oesophagus, stomach, live...
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Article
Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers
It is estimated that cigarette smoking kills over 1 000 000 people each year by causing lung cancer as well as many other neoplasmas. p53 mutations are frequent in tobacco-related cancers and the mutation load...