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  1. No Access

    Article

    Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention

    Tobacco products present a deadly combination of nicotine addiction and carcinogen exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless tobacco products lead to unaccepta...

    Stephen S. Hecht, Dorothy K. Hatsukami in Nature Reviews Cancer (2022)

  2. Article

    Open Access

    Advancing equity, diversity, and inclusion in the American College of Neuropsychopharmacology (ACNP): advances, challenges, and opportunities to accelerate progress

    It is increasingly accepted that higher levels of excellence and innovation in research can be achieved by organizations that promote equity, diversity, and inclusion across several domains including ethnicity...

    Jack E. Henningfield, Sherecce Fields, James C. Anthony in Neuropsychopharmacology (2021)

  3. No Access

    Article

    Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers

    It is unclear why Black smokers in the United States have elevated risk of some tobacco-related diseases compared to White smokers. One possible causal mechanism is differential intake of tobacco toxicants, bu...

    Gideon St.Helen, Neal L. Benowitz in Journal of Exposure Science & Environmenta… (2021)

  4. Article

    Open Access

    Tobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers

    The Multiethnic Cohort Study has demonstrated that African Americans and Native Hawaiians have a higher risk for lung cancer due to cigarette smoking than Whites while Latinos and Japanese Americans have a low...

    Sharon E. Murphy, Sungshim Lani Park, Silvia Balbo in npj Precision Oncology (2018)

  5. No Access

    Article

    Persistence and amplitude of cigarette demand in relation to quit intentions and attempts

    The cigarette purchase task (CPT) is a method that can be used to assess the relative value of cigarettes. Based on cigarettes purchased across a price range, five derived metrics (Omax, Pmax, breakpoint, inte...

    Richard J. O’Connor, Bryan W. Heckman, Sarah E. Adkison in Psychopharmacology (2016)

  6. No Access

    Article

    Changes in circulating leptin levels during the initial stage of cessation are associated with smoking relapse

    Leptin has been linked to tobacco craving and withdrawal-related symptoms. Very few studies have examined leptin prospectively in both male and female nonsmokers and smokers.

    Andrine Lemieux, Motohiro Nakajima, Dorothy K. Hatsukami in Psychopharmacology (2015)

  7. No Access

    Article

    Very Low Nicotine Content Cigarettes and Potential Consequences on Cardiovascular Disease

    Cigarette smoking remains highly prevalent in the U.S. and contributes significantly to cardiovascular disease (CVD). Tobacco control policies, including product regulation, can reduce smoking-related harm. On...

    Danielle L. Joel, Rachel L. Denlinger in Current Cardiovascular Risk Reports (2012)

  8. No Access

    Article

    Chemoprevention of lung carcinogenesis in addicted smokers and ex-smokers

  9. Lung cancer kills more than 3,000 people every day, and most of this toll is due to cigarette smoking. Although tobacco control is clearly the most desirable w...

  10. Stephen S. Hecht, Fekadu Kassie, Dorothy K. Hatsukami in Nature Reviews Cancer (2009)

  11. No Access

    Article

    Pharmacological and Behavioral Strategies for Smoking Cessation

    After over two decades of intensive research, a variety of smoking cessation strategies, both behavioral and pharmacotherapeutic, have been developed and clinically validated. In this review, pha...

    Dorothy K. Hatsukami, Marc E. Mooney in Journal of Clinical Psychology in Medical Settings (1999)

  12. No Access

    Article

    Characterization of tobacco withdrawal symptoms: transdermal nicotine reduces hunger and weight gain

    The accurate assessment of both tobacco withdrawal and the impact of the nicotine patch on withdrawal may be compromised by attrition of subjects, or by subjects smoking during withdrawal. To reduce these occ...

    D. E. Jorenby, Dorothy K. Hatsukami, Stevens S. Smith in Psychopharmacology (1996)

  13. Article

    Tobacco withdrawal symptoms: an experimental analysis

    Dorothy K. Hatsukami, John R. Hughes, Roy W. Pickens, Dean Svikis in Psychopharmacology (1992)

  14. No Access

    Article

    Situational factors and patterns associated with smokeless tobacco use

    Situational factors and topographic features associated with smokeless tobacco use were examined. Male smokeless tobacco users (N=30) were asked to record the time, activity, and internal states associated wit...

    Dorothy K. Hatsukami, Deborah Anton, Allan Callies in Journal of Behavioral Medicine (1991)

  15. No Access

    Article

    Signs and symptoms from nicotine gum abstinence

    This study examined and compared withdrawal signs and symptoms from cessation of 0, 2 and 4 mg nicotine gum. In addition, a comparison was made between nicotine gum versus cigarette withdrawal symptoms. Smoker...

    Dorothy K. Hatsukami, Kelli Skoog, Marguerite Huber, John Hughes in Psychopharmacology (1991)

  16. No Access

    Article

    The relationship between chronic ethanol exposure and cigarette smoking in the laboratory and the natural environment

    Few studies have examined the association between ethanol use and cigarette smoking topography. In particular, no study has objectively investigated the relationship between chronic ethanol exposure and cigare...

    Robert M. Keenan, Dorothy K. Hatsukami, Roy W. Pickens in Psychopharmacology (1990)

  17. No Access

    Article

    The effects of short-term smokeless tobacco deprivation on performance

    Several past studies have reported reliable changes in reaction time performance and self-rated withdrawal scores as a consequence of cigarette deprivation. The purpose of the present study was to determine, p...

    Robert M. Keenan, Dorothy K. Hatsukami, Deborah J. Anton in Psychopharmacology (1989)

  18. No Access

    Article

    Topographical features of smokeless tobacco use

    There is an increasing prevalence of smokeless tobacco use. However, very little descriptive information is available on the pattern of use. This study examines topographical features of smokeless tobacco use ...

    Dorothy K. Hatsukami, Robert M. Keenan, Deborah J. Anton in Psychopharmacology (1988)

  19. No Access

    Article

    Symptoms of tobacco withdrawal from total cigarette cessation versus partial cigarette reduction

    The study examined the occurrence of acute tobacco withdrawal symptoms among three methods of smoking cessation. Smokers were asked to smoke ad lib for 3 days and then randomly assigned to one of three groups ...

    Dorothy K. Hatsukami, Lisa Dahlgren, Robert Zimmerman, John R. Hughes in Psychopharmacology (1988)

  20. No Access

    Article

    Tobacco withdrawal symptoms: An experimental analysis

    This study was a prospective examination of tobacco withdrawal symptoms in a controlled environment. Smokers (N=27) were hospitalized for a 7-day period during which a battery of tests was administered. Smokers w...

    Dorothy K. Hatsukami, John R. Hughes, Roy W. Pickens, Dace Svikis in Psychopharmacology (1984)

  21. No Access

    Article

    Effect of nicotine on the tobacco withdrawal syndrome

    This study tested the ability of nicotine to alleviate the tobacco withdrawal syndrome. Signs and symptoms of tobacco withdrawal were measured in 100 smokers who fulfilled DSM-III criteria for tobacco dependen...

    John R. Hughes, Dorothy K. Hatsukami, Roy W. Pickens, Dean Krahn in Psychopharmacology (1984)