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Article
Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention
Tobacco products present a deadly combination of nicotine addiction and carcinogen exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless tobacco products lead to unaccepta...
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Article
Open AccessAdvancing equity, diversity, and inclusion in the American College of Neuropsychopharmacology (ACNP): advances, challenges, and opportunities to accelerate progress
It is increasingly accepted that higher levels of excellence and innovation in research can be achieved by organizations that promote equity, diversity, and inclusion across several domains including ethnicity...
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Article
Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers
It is unclear why Black smokers in the United States have elevated risk of some tobacco-related diseases compared to White smokers. One possible causal mechanism is differential intake of tobacco toxicants, bu...
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Article
Open AccessTobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers
The Multiethnic Cohort Study has demonstrated that African Americans and Native Hawaiians have a higher risk for lung cancer due to cigarette smoking than Whites while Latinos and Japanese Americans have a low...
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Article
Persistence and amplitude of cigarette demand in relation to quit intentions and attempts
The cigarette purchase task (CPT) is a method that can be used to assess the relative value of cigarettes. Based on cigarettes purchased across a price range, five derived metrics (Omax, Pmax, breakpoint, inte...
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Article
Changes in circulating leptin levels during the initial stage of cessation are associated with smoking relapse
Leptin has been linked to tobacco craving and withdrawal-related symptoms. Very few studies have examined leptin prospectively in both male and female nonsmokers and smokers.
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Article
Very Low Nicotine Content Cigarettes and Potential Consequences on Cardiovascular Disease
Cigarette smoking remains highly prevalent in the U.S. and contributes significantly to cardiovascular disease (CVD). Tobacco control policies, including product regulation, can reduce smoking-related harm. On...
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Article
Chemoprevention of lung carcinogenesis in addicted smokers and ex-smokers
Lung cancer kills more than 3,000 people every day, and most of this toll is due to cigarette smoking. Although tobacco control is clearly the most desirable w...
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Article
Pharmacological and Behavioral Strategies for Smoking Cessation
After over two decades of intensive research, a variety of smoking cessation strategies, both behavioral and pharmacotherapeutic, have been developed and clinically validated. In this review, pha...
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Article
Characterization of tobacco withdrawal symptoms: transdermal nicotine reduces hunger and weight gain
The accurate assessment of both tobacco withdrawal and the impact of the nicotine patch on withdrawal may be compromised by attrition of subjects, or by subjects smoking during withdrawal. To reduce these occ...
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Article
Tobacco withdrawal symptoms: an experimental analysis
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Article
Situational factors and patterns associated with smokeless tobacco use
Situational factors and topographic features associated with smokeless tobacco use were examined. Male smokeless tobacco users (N=30) were asked to record the time, activity, and internal states associated wit...
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Article
Signs and symptoms from nicotine gum abstinence
This study examined and compared withdrawal signs and symptoms from cessation of 0, 2 and 4 mg nicotine gum. In addition, a comparison was made between nicotine gum versus cigarette withdrawal symptoms. Smoker...
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Article
The relationship between chronic ethanol exposure and cigarette smoking in the laboratory and the natural environment
Few studies have examined the association between ethanol use and cigarette smoking topography. In particular, no study has objectively investigated the relationship between chronic ethanol exposure and cigare...
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Article
The effects of short-term smokeless tobacco deprivation on performance
Several past studies have reported reliable changes in reaction time performance and self-rated withdrawal scores as a consequence of cigarette deprivation. The purpose of the present study was to determine, p...
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Article
Topographical features of smokeless tobacco use
There is an increasing prevalence of smokeless tobacco use. However, very little descriptive information is available on the pattern of use. This study examines topographical features of smokeless tobacco use ...
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Symptoms of tobacco withdrawal from total cigarette cessation versus partial cigarette reduction
The study examined the occurrence of acute tobacco withdrawal symptoms among three methods of smoking cessation. Smokers were asked to smoke ad lib for 3 days and then randomly assigned to one of three groups ...
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Tobacco withdrawal symptoms: An experimental analysis
This study was a prospective examination of tobacco withdrawal symptoms in a controlled environment. Smokers (N=27) were hospitalized for a 7-day period during which a battery of tests was administered. Smokers w...
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Effect of nicotine on the tobacco withdrawal syndrome
This study tested the ability of nicotine to alleviate the tobacco withdrawal syndrome. Signs and symptoms of tobacco withdrawal were measured in 100 smokers who fulfilled DSM-III criteria for tobacco dependen...