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  1. Article

    Open Access

    An ultra high-endurance memristor using back-end-of-line amorphous SiC

    Integrating resistive memory or neuromorphic memristors into mainstream silicon technology can be substantially facilitated if the memories are built in the back-end-of-line (BEOL) and stacked directly above t...

    Omesh Kapur, Dongkai Guo, Jamie Reynolds, Daniel Newbrook, Yisong Han in Scientific Reports (2024)

  2. Article

    Open Access

    The impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities

    The telomere repetitive TTAGGG motif at the ends of chromosomes, serves to preserve genomic integrity and chromosomal stability. In turn, genomic instability is a hallmark of cancer—implicating telomere distur...

    Ruotian Huang, M. S. Riana Bornman, Phillip D. Stricker in Scientific Reports (2024)

  3. Article

    Open Access

    Laparoscopic ureteroneocystostomy with bladder flap for benign ureteral stenosis: our initial experience

    To present our experience with laparoscopic ureteroneocystostomy with bladder flap (LUCBF) for treating benign ureteral stenosis and evaluate its feasibility and efficacy. The clinical data of 27 patients with...

    Zhaolin Zhang, Ruohui Huang, Tianpeng **e, Qingming Zeng, Linwei Liu in Scientific Reports (2024)

  4. Article

    Open Access

    Design of combination therapy for engineered bacterial therapeutics in non-small cell lung cancer

    Synthetic biology enables the engineering of bacteria to safely deliver potent payloads to tumors for effective anti-cancer therapies. However, a central challenge for translation is determining ideal bacteria...

    Dhruba Deb, Yangfan Wu, Courtney Coker, Tetsuhiro Harimoto in Scientific Reports (2022)

  5. Article

    Open Access

    Identifying the long-term survival beneficiary of chemotherapy for stage N1c sigmoid colon cancer

    Sigmoid colon cancer often has an unsatisfactory prognosis. This study explored the effect of tumor deposits (TDs) on survival, and whether their presence/absence influence individualized treatment. Data of po...

    Shan Liu, Yaobin Lin, Sihan Huang, Shufang Xue, Ruoyao Huang, Lu Chen in Scientific Reports (2022)

  6. Article

    Open Access

    Systematic strategies for develo** phage resistant Escherichia coli strains

    Phages are regarded as powerful antagonists of bacteria, especially in industrial fermentation processes involving bacteria. While bacteria have developed various defense mechanisms, most of which are effectiv...

    Xuan Zou, **aohong **ao, Ziran Mo, Yashi Ge, **ng Jiang in Nature Communications (2022)

  7. Article

    Open Access

    Poly(N-isopropylacrylamide) based thin microgel films for use in cell culture applications

    Poly(N-isopropylacrylamide) (PNIPAm) is widely used to fabricate cell sheet surfaces for cell culturing, however copolymer and interpenetrated polymer networks based on PNIPAm have been rarely explored in the ...

    Ilaria Sanzari, Elena Buratti, Ruomeng Huang, Camelia G. Tusan in Scientific Reports (2020)

  8. Article

    Open Access

    Effects of palmatine on BDNF/TrkB-mediated trigeminal neuralgia

    Trigeminal neuralgia (TN), a sudden, needle-like pain in the distribution area of the trigeminal nerve, can seriously affect the physical and mental health of patients. In chronic pain conditions including TN,...

    Lijuan Liu, Lingkun He, Cancan Yin, Ruoyu Huang, Wenhao Shen in Scientific Reports (2020)

  9. Article

    Open Access

    Dihydromyricetin affects BDNF levels in the nervous system in rats with comorbid diabetic neuropathic pain and depression

    Diabetic neuropathic pain (DNP) and depression (DP) are the common complications in patients with diabetes. The purpose of our research was to observe whether brain-derived neurotrophic factor (BDNF) levels an...

    Huixiang Ge, Shu Guan, Yulin Shen, Mengyun Sun, Yuanzhen Hao in Scientific Reports (2019)

  10. Article

    Open Access

    Gene Expression and Methylation Analyses Suggest DCTD as a Prognostic Factor in Malignant Glioma

    Malignant glioma is the most common brain cancer with dismal outcomes. Individual variation of the patients’ survival times is remarkable. Here, we investigated the transcriptome and promoter methylation diffe...

    Huimin Hu, Zheng Wang, Mingyang Li, Fan Zeng, Kuanyu Wang in Scientific Reports (2017)

  11. Article

    Open Access

    Nanoscale arrays of antimony telluride single crystals by selective chemical vapor deposition

    Arrays of individual single nanocrystals of Sb2Te3 have been formed using selective chemical vapor deposition (CVD) from a single source precursor. Crystals are self-assembled reproducibly in confined spaces of 1...

    Ruomeng Huang, Sophie L. Benjamin, Chitra Gurnani, Yudong Wang in Scientific Reports (2016)