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Chapter and Conference Paper
Carcinogenic Effects in Rats of Exposure to Different Minerals from Metallic Mine Ores, Radon and Radon Daughters
Combined exposure to radon and mineral dust is very common in some mine environments. It has been suggested that the carcinogenic activity of some inorganic materials might be related to their surface reducing...
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Chapter and Conference Paper
Unscheduled DNA synthesis (UDS) induced in vitro by cadmium in tracheal epithelial cells of rat and hamster
Cadmium (Cd) is an ubiquitous pollutant of industry and environment. It is known to damage various organs such as bones, lungs and kidneys in m a n and experimental animals (Paterson 1947; Friberg et al., 1986...
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Article
Multiplicative effect of inhaled plutonium oxide and benzo (a) pyrene on lung carcinogenesis in rats
This study describes the effect of intratracheal instillations (2 X 5 mg) of benzo(a)pyrene (B(a)P) on lung carcinogenesis in rats which had previously inhaled different levels of 239 plutonium oxide (220, 630...
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Chapter
Lung Carcinogenesis During in Vivo Cigarette Smoking and Radon Daughter Exposure in Rats
The carcinogenic activity of tobacco smoke is clearly demonstrated by human epidemiologic data. Whereas in experimental animals tracheobronchial applications or injections of tars produce cancerous lesions, in...
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Article
Bone tumours induced in rats with radioactive cerium
A technique is described for the induction of metastasizing bone tumours in rats by local inoculation of 144cerium. Bone sarcomas develop in 90% of the animals and 74% of these had lung metastases. The tumours...
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Chapter
Modulation of Tumor Growth and Metastasis by an Acute Inflammation
Many studies have led to the conclusion that macrophage can contribute in a variety of ways to host resistance against tumors. Non immune inflammation represents the major mechanism by which indirect activatio...
