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  1. Article

    Open Access

    Transcriptomics and metabolomics reveal hypothalamic metabolic characteristics and key genes after subarachnoid hemorrhage in rats

    Subarachnoid hemorrhage (SAH) is a serious hemorrhagic event with high mortality and morbidity. Multiple injurious events produced by SAH can lead to a series of pathophysiologic processes in the hypothalamus ...

    Zongchi Liu, Zhaohui Chai, Fan Wu, Luyuan Zhang, **aoyi Wang in Metabolic Brain Disease (2024)

  2. Article

    Correction to: MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening

    Guangsuo **ng, Zichao Liu, Luyuan Huang, Danyun Zhao in Cell Death & Differentiation (2022)

  3. No Access

    Article

    Homologous Expression and Characterization of α-L-rhamnosidase from Aspergillus niger for the Transformation of Flavonoids

    Aspergillus niger has been used for homologous and heterologous expressions of many protein products. In this study, the α-L-rhamnosidase from A. niger (Rha-N1, GenBank XP_001389086.1) was homologously expressed ...

    Hangyu Ye, **aojun Li, Luyuan Li, Yinjun Zhang in Applied Biochemistry and Biotechnology (2022)

  4. No Access

    Article

    MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening

    Somatic cell reprogramming is an ideal model for studying epigenetic regulation as it undergoes dramatic chromatin remodeling. However, a role for phosphorylation signaling in chromatin protein modifications f...

    Guangsuo **ng, Zichao Liu, Luyuan Huang, Danyun Zhao in Cell Death & Differentiation (2022)

  5. Article

    Correction to: Quantification and toxicokinetics of paraquat in mouse plasma and lung tissues by internal standard surface enhanced Raman spectroscopy

    Luyuan Qin, **aomin Zhang, Jianfeng Wu in Analytical and Bioanalytical Chemistry (2022)

  6. No Access

    Article

    Quantification and toxicokinetics of paraquat in mouse plasma and lung tissues by internal standard surface-enhanced Raman spectroscopy

    Paraquat is a quaternary ammonium herbicide with an excellent herbicidal effect but is highly toxic to human and animals. Although prohibited by many countries, paraquat intoxication occurred occasionally and ...

    Luyuan Qin, **aomin Zhang, Jianfeng Wu in Analytical and Bioanalytical Chemistry (2022)

  7. No Access

    Article

    Effect of Coformer Selection on In Vitro and In Vivo Performance of Adefovir Dipivoxil Cocrystals

    This study aimed to improve the in vitro dissolution, permeability and oral bioavailability of adefovir dipivoxil (ADD) by cocrystal technology and clarify the important role of coformer selection on the cocrysta...

    Luyuan Li, Zunting Pang, Kun Ma, Yuan Gao, Daoyi Zheng in Pharmaceutical Research (2021)

  8. Article

    Open Access

    SRSF1 promotes the inclusion of exon 3 of SRA1 and the invasion of hepatocellular carcinoma cells by interacting with exon 3 of SRA1pre-mRNA

    Steroid receptor RNA activator 1 (SRA1) has been described as a novel transcriptional co-activator that affects the migration of cancer cells. Through RT-PCR, we identified that skip** exon 3 of SRA1 produces t...

    Sijia Lei, Bin Zhang, Luyuan Huang, Ziyou Zheng, Shaohan **e in Cell Death Discovery (2021)

  9. No Access

    Article

    Engineering the regulatory site of the catalase promoter for improved heterologous protein production in Pichia pastoris

    To build a stronger Pichia pastoris PCAT1 promoter and to identify putative transcriptional factor binding sites (TFBSs) on PCAT1 that affect the activity of the promoter.

    Luyuan Nong, Yiming Zhang, Yehong Duan, Shulin Hu, Ying Lin in Biotechnology Letters (2020)

  10. No Access

    Article

    Hydrogel-based microbeads for Raman-encoded suspension array using the reversed-phase suspension polymerization method and ultraviolet light curing

    A one-step synthesis using the reversed-phase suspension polymerization method and ultraviolet light curing is proposed for preparing the Raman-encoded suspension array (SA). The encoded microcarriers are prep...

    Xue**g Chen, Xuesi Zhou, Qinghua He, Yonghong He in Analytical and Bioanalytical Chemistry (2020)

  11. Article

    Open Access

    Circular RNA hsa_circ_001783 regulates breast cancer progression via sponging miR-200c-3p

    Increasing evidence suggests circular RNAs (circRNAs) exert critical functions in tumor progression via sponging miRNAs (microRNAs). However, the role of circRNAs in breast cancer remains unclear. Here we syst...

    Zihao Liu, You Zhou, Gehao Liang, Yun Ling, Weige Tan, Luyuan Tan in Cell Death & Disease (2019)

  12. Article

    Open Access

    SFRP2 enhances the osteogenic differentiation of apical papilla stem cells by antagonizing the canonical WNT pathway

    Exploring the molecular mechanisms underlying directed differentiation is helpful in the development of clinical applications of mesenchymal stem cells (MSCs). Our previous study on dental tissue-derived MSCs ...

    Luyuan **, Yu Cao, Guoxia Yu, **song Wang in Cellular & Molecular Biology Letters (2017)

  13. No Access

    Article

    Diachronic analysis of genetic diversity in rice landraces under on-farm conservation in Yunnan, China

    Diachronic analysis showed no significant changes in the level of genetic diversity occurred over the past 27 years’ domestication, which indicated genetic diversity was successfully maintained...

    Di Cui, **mei Li, Cuifeng Tang, **nxiang A in Theoretical and Applied Genetics (2016)

  14. No Access

    Article

    A recombinant trans-membrane protein hMnSOD–R9 inhibits the proliferation of cervical cancer cells in vitro

    Human manganese superoxide dismutase (hMnSOD) is a new type of cancer suppressor. Nonamer of arginine (R9) is an efficient protein transduction domain (PTD). The aim of the study was to improve the transductio...

    Zide Zhang, Luyuan Huang, Qiuhong Wu, Enze Yang in Molecular and Cellular Biochemistry (2014)

  15. No Access

    Article

    The First Tian** Forum on Tumor Microenvironment Tian**, China, July 2–4, 2010

    Luyuan Li in Cancer Microenvironment (2010)

  16. No Access

    Article

    Cloning and expression of a luxRhomologue from Xanthomonas oryzae pv. oryzae

    LuxR homologues are the main components of LuxR/LuxI circuit in Quorum Sensing (QS) of Gram-negative bacteria. A luxR homologue, designated as xooR, was cloned from X. oryzae pv. oryzae. The xooR gene is a trans...

    Bin Liang, Bin Guo, Chen Yang, **njun Zhang, Luyuan Dai in Frontiers of Biology in China (2006)