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  1. No Access

    Article

    Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pKa Rule

    Honokiol (HK), a BCS class II drug with a wide range of pharmacological activities, has poor solubility and low oral bioavailability, severely limiting its clinical application. In the current study, incorpora...

    **aoshuang He, Yuanfeng Wei, Shiru Wang, Jianjun Zhang, Yuan Gao… in Pharmaceutical Research (2022)

  2. No Access

    Article

    Effect of Coformer Selection on In Vitro and In Vivo Performance of Adefovir Dipivoxil Cocrystals

    This study aimed to improve the in vitro dissolution, permeability and oral bioavailability of adefovir dipivoxil (ADD) by cocrystal technology and clarify the important role of coformer selection on the cocrysta...

    Luyuan Li, Zunting Pang, Kun Ma, Yuan Gao, Daoyi Zheng… in Pharmaceutical Research (2021)