10 Result(s)
within
Juan Antonio Rodríguez
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Article
Open AccessA multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer
Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% ...
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Article
Reply to: Retesting the influences of mutation accumulation and antagonistic pleiotropy on human senescence and disease
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Chapter and Conference Paper
University Workshops as a Way of Dissemination of Architectural Traditions: The Case of the Tile Vault
University workshops about traditional construction systems have proven an interesting tool for the contemporary dissemination of architectural traditions. These workshops commonly seek to revitalize abandoned...
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Article
Antagonistic pleiotropy and mutation accumulation influence human senescence and disease
Senescence has long been a public health challenge as well as a fascinating evolutionary problem. There is neither a universally accepted theory for its ultimate causes, nor a consensus about what may be its i...
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Article
Open AccessCombining Multiple Hypothesis Testing with Machine Learning Increases the Statistical Power of Genome-wide Association Studies
The standard approach to the analysis of genome-wide association studies (GWAS) is based on testing each position in the genome individually for statistical significance of its association with the phenotype u...
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Article
Open AccessGenomic analysis of the blood attributed to Louis XVI (1754–1793), king of France
A pyrographically decorated gourd, dated to the French Revolution period, has been alleged to contain a handkerchief dipped into the blood of the French king Louis XVI (1754–1793) after his beheading but recen...
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Article
Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European
A complete pre-agricultural European human genome from a ∼7,000-year-old Mesolithic skeleton suggests the existence of a common genomic signature across western and central Eurasia from the Upper Paleolithic t...
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Chapter and Conference Paper
Develo** Virtual Heritage Applications as Normative Multiagent Systems
The majority of existing virtual heritage applications are focused on detailed 3D reconstruction of historically significant sites and ancient artifacts. Recreating the way of life of ancient people is only co...
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Chapter and Conference Paper
A Novel Hierarchical Framework for Object-Based Visual Attention
This paper proposes an artificial visual attention model which builds a saliency map associated to the sensed scene using a novel perception-based grou** process. This grou** mechanism is performed by a hi...
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Chapter and Conference Paper
Neural Networks & Antennas Design: an Application for Avoiding Interferences
The presence of interferences is an usual problem when somebody is working with antennas. In order to alleviate their effects, it is common to lessen the received energy in the direction of arrival of this unw...
