Skip to main content

7 Result(s)

within J. Lafuma Remove this filter

and

  1. No Access

    Article

    Analysis of lung tumour risk in radon-exposed rats: an intercomparison of multi-step modelling

    Three carcinogenesis modelling groups have both jointly and separately applied a multi-step carcinogenesis model with clonal expansion to one data set of lung tumours in rats exposed to radon (CEA, France). Th...

    W. F. Heidenreich, M. J. P. Brugmans… in Radiation and Environmental Biophysics (2000)

  2. No Access

    Chapter

    Cocarcinogenic Effect of Tobacco Smoke in Rats

    The use of an animal model for investigating the induction of lung cancer by tobacco smoke in man is open to many objections, and epidemiology has already established a connection. Society might therefore rega...

    R. Masse, J. Chameaud, J. Lafuma in Smoking and the Lung (1984)

  3. No Access

    Chapter

    Effect of Chronic Administration of a Synthetic Aromatic Retinoid (Ro 10-9359) on the Development of Lung Squamous Metaplasia and Epidermoid Cancer in Rats

    Since the first studies of Saffioti et al. (1) suggesting the preventive effect of high doses of vitamin A on squamous metaplasias of trachea and bronchis, several authors have used synthetic analogs of vitami...

    D. Nolibe, R. Masse, J. Lafuma, I. Florentin in Biological Response Modifiers in Human Onc… (1983)

  4. No Access

    Chapter

    Lung Carcinogenesis During in Vivo Cigarette Smoking and Radon Daughter Exposure in Rats

    The carcinogenic activity of tobacco smoke is clearly demonstrated by human epidemiologic data. Whereas in experimental animals tracheobronchial applications or injections of tars produce cancerous lesions, in...

    J. Chameaud, R. Perraud, J. Chrétien… in Early Detection and Localization of Lung T… (1982)

  5. No Access

    Article

    Bone tumours induced in rats with radioactive cerium

    A technique is described for the induction of metastasizing bone tumours in rats by local inoculation of 144cerium. Bone sarcomas develop in 90% of the animals and 74% of these had lung metastases. The tumours...

    H G Delbrück, M Allouche, C Jasmin, M Morin, F Deml… in British Journal of Cancer (1980)

  6. No Access

    Article

    Metabolic and dosimetric studies after inhalation of227Th in rats with regard to the risk of lung and bone tumors

    227Th (α-emitter, half-life 18.7 days) was inhaled by rats from solution in nitrate form. Organ doses were calculated after whole body measurements and measuring of activity concentrations in the organs over a l...

    Dr. W. A. Müller, J. C. Nenot, M. L. Daburon… in Radiation and Environmental Biophysics (1975)

  7. No Access

    Chapter

    Lesions and Lung Cancers Induced in Rats by Inhaled Radon 222 at Various Equilibriums with Radon Daughters

    To investigate the dose-effect relationships, rats were exposed to several dose levels of radon at different levels of equilibrium with radon decay products, after inhalation of stable cerium hydroxide, and in...

    J. Chameaud, R. Perraud, J. LaFuma, R. Masse, J. Pradel in Experimental Lung Cancer (1974)