![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Chapter
Micellar-Based Nanoparticles for Cancer Therapy and Bioimaging
Micelles are versatile nanosized systems composed by amphiphilic molecules. Their small size and capacity to encapsulate both hydrophilic and hydrophobic compounds, as well as their easier functionalization, a...
-
Article
Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization
The freezing step in lyophilization is the most determinant for the quality of biopharmaceutics. Using insulin as model of therapeutic protein, our aim was to evaluate the freezing effect in the stability and ...
-
Article
Biodistribution and Pharmacokinetics of Dapivirine-Loaded Nanoparticles after Vaginal Delivery in Mice
To assess the potential of polymeric nanoparticles (NPs) to affect the genital distribution and local and systemic pharmacokinetics (PK) of the anti-HIV microbicide drug candidate dapivirine after vaginal deli...
-
Chapter
Pulmonary Delivery of Biopharmaceuticals
Biopharmaceuticals are in the most cases used at hospital and health care units due to the necessity of parenteral administration by specialized personnel. Others like insulin could be administered by the pati...