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  1. No Access

    Chapter

    Micellar-Based Nanoparticles for Cancer Therapy and Bioimaging

    Micelles are versatile nanosized systems composed by amphiphilic molecules. Their small size and capacity to encapsulate both hydrophilic and hydrophobic compounds, as well as their easier functionalization, a...

    Fernanda Andrade, Andreia Almeida, Diana Rafael, Simo Schwartz Jr… in Nanooncology (2018)

  2. No Access

    Article

    Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization

    The freezing step in lyophilization is the most determinant for the quality of biopharmaceutics. Using insulin as model of therapeutic protein, our aim was to evaluate the freezing effect in the stability and ...

    Pedro Fonte, Fernanda Andrade, Cláudia Azevedo, João Pinto… in Pharmaceutical Research (2016)

  3. No Access

    Article

    Biodistribution and Pharmacokinetics of Dapivirine-Loaded Nanoparticles after Vaginal Delivery in Mice

    To assess the potential of polymeric nanoparticles (NPs) to affect the genital distribution and local and systemic pharmacokinetics (PK) of the anti-HIV microbicide drug candidate dapivirine after vaginal deli...

    José das Neves, Francisca Araújo, Fernanda Andrade… in Pharmaceutical Research (2014)

  4. No Access

    Chapter

    Pulmonary Delivery of Biopharmaceuticals

    Biopharmaceuticals are in the most cases used at hospital and health care units due to the necessity of parenteral administration by specialized personnel. Others like insulin could be administered by the pati...

    Fernanda Andrade, Catarina Moura, Bruno Sarmento in Mucosal Delivery of Biopharmaceuticals (2014)