11 Result(s)

Article

Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

Hanane Laklai, Yekaterina A. Miroshnikova, Michael W. Pickup… in Nature Medicine (2024)

Article

Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Yu Shi, Weina Gao, Nikki K. Lytle, Peiwu Huang, **ao Yuan, Amanda M. Dann… in Nature (2021)

Article

Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer

KRAS mutations are present in over 90% of pancreatic ductal adenocarcinomas (PDAC), and drive their poor outcomes and failure to respond to targeted therapies. Here we show that Leukemia Inhibitory Factor (LIF...

Man-Tzu Wang, Nicole Fer, Jacqueline Galeas, Eric A. Collisson… in Nature Communications (2019)

Article

Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma

Sebaceous carcinomas (SeC) are cutaneous malignancies that, in rare cases, metastasize and prove fatal. Here we report whole-exome sequencing on 32 SeC, revealing distinct mutational classes that explain both ...

Jeffrey P. North, Justin Golovato, Charles J. Vaske… in Nature Communications (2018)

Article

Erratum to: Modeling precision treatment of breast cancer

During the type-setting of the final version of the article [1] some of the additional files were swapped. The correct files are republished in this Erratum.

Anneleen Daemen, Obi L Griffith, Laura M Heiser, Nicholas J Wang… in Genome Biology (2015)

Article

Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls

Circulating biomarkers are urgently needed in hepatocellular carcinoma (HCC). The aims of this study were to determine the feasibility of detecting and isolating circulating tumor cells (CTCs) in HCC patients ...

Robin K Kelley, Mark Jesus M Magbanua, Timothy M Butler, Eric A Collisson… in BMC Cancer (2015)

Article

Modeling precision treatment of breast cancer

First-generation molecular profiles for human breast cancers have enabled the identification of features that can predict therapeutic response; however, little is known about how the various data types can bes...

Anneleen Daemen, Obi L Griffith, Laura M Heiser, Nicholas J Wang… in Genome Biology (2013)

Article

A robust prognostic signature for hormone-positive node-negative breast cancer

Systemic chemotherapy in the adjuvant setting can cure breast cancer in some patients that would otherwise recur with incurable, metastatic disease. However, since only a fraction of patients would have recurr...

Obi L Griffith, François Pepin, Oana M Enache, Laura M Heiser… in Genome Medicine (2013)

Article

The Cancer Genome Atlas Pan-Cancer analysis project

Current clinical practice is organized according to tissue or organ of origin of tumors. Now, The Cancer Genome Atlas (TCGA) Research Network has started to identify genomic and other molecular commonalities a...

John N Weinstein, Eric A Collisson, Gordon B Mills, Kenna R Mills Shaw… in Nature Genetics (2013)

Article

Timing chromosomal abnormalities using mutation data

Steffen Durinck, Christine Ho, Nicholas J Wang, Wilson Liao… in Genome Biology (2011)

Article

Timing chromosomal abnormalities using mutation data

Steffen Durinck, Christine Ho, Nicholas J Wang, Wilson Liao… in Genome Biology (2011)