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Open AccessA method for intelligent allocation of diagnostic testing by leveraging data from commercial wearable devices: a case study on COVID-19
Mass surveillance testing can help control outbreaks of infectious diseases such as COVID-19. However, diagnostic test shortages are prevalent globally and continue to occur in the US with the onset of new COV...
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Article
Noncanonical open reading frames encode functional proteins essential for cancer cell survival
Although genomic analyses predict many noncanonical open reading frames (ORFs) in the human genome, it is unclear whether they encode biologically active proteins. Here we experimentally interrogated 553 candi...
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Open AccessReply: Matters Arising ‘Investigating sources of inaccuracy in wearable optical heart rate sensors’
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Article
Author Correction: Cas9 activates the p53 pathway and selects for p53-inactivating mutations
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Cas9 activates the p53 pathway and selects for p53-inactivating mutations
Cas9 is commonly introduced into cell lines to enable CRISPR–Cas9-mediated genome editing. Here, we studied the genetic and transcriptional consequences of Cas9 expression itself. Gene expression profiling of ...
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Article
Open AccessErratum to: Modeling precision treatment of breast cancer
During the type-setting of the final version of the article [1] some of the additional files were swapped. The correct files are republished in this Erratum.
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Article
Open AccessModeling precision treatment of breast cancer
First-generation molecular profiles for human breast cancers have enabled the identification of features that can predict therapeutic response; however, little is known about how the various data types can bes...
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Article
Open AccessA robust prognostic signature for hormone-positive node-negative breast cancer
Systemic chemotherapy in the adjuvant setting can cure breast cancer in some patients that would otherwise recur with incurable, metastatic disease. However, since only a fraction of patients would have recurr...
