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Article
Correction: Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa
The fortieth author’s name was listed incorrectly. The correct presentation is A Keski-Rahkonen.
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Article
Open AccessInvestigation of common, low-frequency and rare genome-wide variation in anorexia nervosa
Anorexia nervosa (AN) is a complex neuropsychiatric disorder presenting with dangerously low body weight, and a deep and persistent fear of gaining weight. To date, only one genome-wide significant locus assoc...
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Article
Bulbusperforation eines 7‑jährigen Kindes durch das „Must-Have Office Toy 2017“
Ein 7‑jähriges Mädchen stellte sich im Notdienst wegen Bulbusperforation mit Irisprolaps und Hornhaut- sowie Sklerawunde am linken Auge vor, verursacht durch einen Handkreisel (englisch: „fidget spinner“). Ein...
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Article
A genome-wide association study of anorexia nervosa
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by dangerously low body weight. Neither candidate gene studies nor an initial genome-wide association study (GWAS) have yielded si...
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Article
The Breast Avastin Trial: phase II study of bevacizumab maintenance therapy after induction chemotherapy with docetaxel and capecitabine for the first-line treatment of patients with locally recurrent or metastatic breast cancer
Therapeutic approach for patients with metastatic breast cancer (MBC) is still controversial. This study was conducted to assess the efficacy and safety of bevacizumab in combination with docetaxel plus capeci...
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Article
Open AccessERCC1/BRCA1 expression and gene polymorphisms as prognostic and predictive factors in advanced NSCLC treated with or without cisplatin
The FAST was a factorial trial in first-line treatment of advanced non-small-cell lung cancer (NSCLC), addressing the role of replacing cisplatin with a non-platinum agent. The prognostic and predictive effect...
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Article
Open AccessTriplets versus doublets, with or without cisplatin, in the first-line treatment of stage IIIB–IV non-small cell lung cancer (NSCLC) patients: a multicenter randomised factorial trial (FAST)
The FAST is a 2 × 2 factorial trial addressing two questions: (1) the role of replacing cisplatin (P) with a non-platinum agent, vinorelbine (N), and (2) the role of adding a third agent, ifosfamide (I), in a ...
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Article
Open AccessSorafenib in patients with advanced biliary tract carcinoma: a phase II trial
Advanced biliary tract carcinoma has a very poor prognosis, with chemotherapy being the mainstay of treatment. Sorafenib, a multikinase inhibitor of VEGFR-2/-3, PDGFR-β, B-Raf, and C-Raf, has shown to be active i...
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Chapter
Ultrasound and Fetal Stress: Study of the Fetal Blink-Startle Reflex Evoked by Acoustic Stimuli
The development of ultrasound techniques opened a window on the prenatal world. Since the early 1990s, bidimensional ultrasonography has played an important role in the study of certain fetal behaviours in att...
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Chapter and Conference Paper
Antiviral Cell-Mediated Immune Responses During Hepatitis B and Hepatitis C Virus Infections
Cell-mediated immune responses to hepatitis B (HBV) and hepatitis C virus (HCV) antigens are vigorous and multispecific in acute, self-limited infections. Moreover, the prevalent cytokine pattern of circulatin...
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Article
Mineral waters in Italy
The use of spring water as a drinking, therapeutic, and ornamental resource has historical origins that date back to the Romans. The most ancient regulations on “mineral waters” had been enacted in Italy long ...
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Article
Water supply of Rome in antiquity and today
In ancient Rome, water was considered a deity to be worshipped and most of all utilized in health and art. The availability of huge water supplies was considered a symbol of opulence and therefore an expressio...
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Chapter
Cell-mediated Immune Response in Hepatitis C Virus (HCV) Infection: Are Different Strategies Adopted by HCV and Hepatitis B Virus to Persist?
Immune-mediated mechanisms play an important role in the pathogenesis of liver cell injury and viral persistence in both HCV and hepatitis B virus (HBV) infections. However, the different vigor of HLA class I ...
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Chapter and Conference Paper
Clinical Evidence of Myocardial Damage in Patients with Acute Subarachnoid Hemorrhage
A high proportion of patients with acute and chronic brain damage such as subarachnoid and intracranial hemorrhage and subdural hematoma [1–5], cerebral thrombosis or embolism [6], meningitis, intracranial spa...
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Article
Analysis of Coal Fly Ash by Bulk and Surface Characterization Techniques
The application of different characterization techniques to the study of coal fly ash formation and of its behaviour in particulate control devices is discussed. Particle Induced X-ray Emission (PIXE) and Prot...
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Chapter
Molecular Genetics of Tyrosine Hydroxylase
The isolation of tyrosine hydroxylase (TH) cDNA clones has allowed the determination of the entire amino acid sequence of this previously uncharacterized protein. Amino acid sequence comparison with phenyl-ala...
