233 Result(s)
-
Article
Biophysical meanings of orientation and deformation of RBCs in shear flow field of low viscosity with new Ektacytometry
The rheological behavior of RBCs treated with WGA of different concentrations was measured by the recently developed new Ektacytometry method in suspending medium of low viscosity. The biophysical meanings of ...
-
Article
Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts
It has been suggested that overexpression of the Bcl-2 oncoprotein in human cancer cells contributes to their resistance to apoptosis induced by chemotherapy. We report here that a novel dipeptidyl proteasome ...
-
Article
The terminal structure plays an important role in the biological activity of cecropin CMIV
Antibacterial peptides have received increasing attention as a new pharmaceutical substance. But the molecular mechanism of lysis is still poorly understood. CMIV gene and mutant CMIV gene in GST fusion system...
-
Article
Function and regulation of Aurora/Ipl1p kinase family in cell division
During mitosis, the parent cell distributes its genetic materials equally into two daughter cells through chromosome segregation, a complex movements orchestrated by mitotic kinases and its effector proteins. ...
-
Article
Dynamic distribution of TTK in HeLa cells: insights from an ultrastructural study
Entry into mitosis is driven by signaling cascades of mitotic kinases. Our recent studies show that TTK, a kinetochore-associated protein kinase, interacts with CENP-E, a mitotic kinesin located to corona fibe...
-
Article
Open AccessPattern similarity study of functional sites in protein sequences: lysozymes and cystatins
Although it is generally agreed that topography is more conserved than sequences, proteins sharing the same fold can have different functions, while there are protein families with low sequence similarity. An ...
-
Article
Cloning and Characterization of a Novel Mouse Short-Chain Dehydrogenases/Reductases cDNA, mHsdl2, Encoding a Protein with an SDR Domain and an SCP2 Domain
The short-chain dehydrogenases/reductases (SDRs) play an important role in the body's metabolism. We have cloned a novel mouse SDR cDNA, which encodes a deduced HSD-like protein with a conserved SDR domain and...
-
Article
Research on cognitive cooperation in multi-agent systems
The accomplishment of a complex problem usually involves cooperation between participators with different knowledge background concerned. This paper identifies interdependency between different sub problems (t...
-
Article
Regulation of MLL1 H3K4 methyltransferase activity by its core components
Histone H3 Lys4 (H3K4) methylation is a prevalent mark associated with transcription activation. A common feature of several H3K4 methyltransferase complexes is the presence of three structural components (RbB...
-
Article
Supplementary data: Assessment of genetic diversity ofLycoris longituba (Amaryllidaceae) detected by RAPDs
-
Article
A fuzzy directed graph-based QoS model for service composition
Web service composition lets developers create applications on top of service-oriented computing and its native description, discovery, and communication capabilities. This paper mainly focuses on the QoS when...
-
Chapter and Conference Paper
Families of FPGA-Based Accelerators for BLAST Algorithm with Multi-seeds Detection and Parallel Extension
As one of the most widely used bio-sequence searching tools, BLAST adopts index-based approach to detect the matches between two substrings by looking up a large table and processing one match per query. In th...
-
Article
Corneal epithelial changes following reconstruction by transplantation of limbal stem cells in goats with total limbal stem cell deficiency
-
Article
Fetal porcine mesenchymal stem cells nuclear transfer and isolation of embryonic stem cells-like derived from cloned blastocysts
-
Article
Characterization of growth and differentiation of goat limbal adult stem cells in vivo and ex vivo
-
Article
Serum free culture and characterization of human embryonic germ cells
-
Article
Isolation and characterization of mouse embryonic stem cell line by parthenogenesis
-
Article
Reconstruction of corneal epithelium with cryopreserved corneal limbal stem cells in a goat model
-
Article
Knock-down Nanog gene expression by siRNA affects the differentiation of cardiomyocytes in P19 cell
-
Article
Transplantation of ex vivo expanded stem cell amniotic sheet for ocular surface reconstruction
