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  1. Article

    Open Access

    Investigations of the functional states of dendritic cells under different conditioned microenvironments by Fourier transformed infrared spectroscopy

    Dendritic cells are potent and specialized antigen presenting cells, which play a crucial role in initiating and amplifying both the innate and adaptive immune responses. The dendritic cell-based vaccination a...

    Rong Dong, **hua Long, **aoli Xu, Chunlin Zhang… in BioMedical Engineering OnLine (2014)

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  2. No Access

    Article

    Effects of Gekko Sulfated Polysaccharide–Protein Complex on the Defective Biorheological Characters of Dendritic Cells Under Tumor Microenvironment

    We previously isolated a sulfated polysaccharide–protein complex from Gekko swinhonis Guenther, a traditional Chinese medicine, and have demonstrated its direct anti-cancer effect on human hepatocellular carcinom...

    Dan Chen, **aolan Zhang, Yuan Du, Binbin Jia, Weibo Ka… in Cell Biochemistry and Biophysics (2012)

  3. No Access

    Article

    Knockdown of hTERT Alters Biophysical Properties of K562 Cells Resulting in Decreased Migration Rate In Vitro

    It has been shown that 90% of tumors, including hematological malignant tumors and leukemia, have much higher levels of telomerase expression than normal cells. To investigate the effect of telomerase on leuke...

    Yingyu Zhang, **aopeng Chen, **aofeng Xu, **anwei Wang… in Cell Biochemistry and Biophysics (2011)

  4. No Access

    Article

    Hepatocellular Carcinoma Cells Deteriorate the Biophysical Properties of Dendritic Cells

    Dendritic cells (DCs) are potent antigen-presenting cells and induce antigen-specific immune responses in the organism. The dysfunction of DCs has been implicated in tumor-bearing host. In order to elucidate t...

    Zhu Zeng, Weijuan Yao, **aofeng Xu, Guoqiang Xu… in Cell Biochemistry and Biophysics (2009)

  5. No Access

    Article

    Effects of TFAR19 gene on the in vivo biorheological properties and pathogenicity of mouse erythroleukemia cell line MEL

    After injecting VP16, MEL cells and MEL-TF19 cells into the body of mice, with those injected with the same dose of saline as the control group, we observed the mice for their blood pictures, histological chan...

    Li Gu, ZhiYu Tang, DongQi He, WeiBo Ka… in Science in China Series C: Life Sciences (2007)

  6. No Access

    Article

    Biochemical and biophysical studies on the precursor cells of mouse erythrocytes at different stages

    The aim of this research is to study the biochemical and biophysical properties of the precursor cells of mouse erythrocytes at different stages and the molecular mechanisms of their regulation. We investigate...

    **hua Wang, Weibo Ka, Dagong Sun, Weijuan Yao… in Cell Biochemistry and Biophysics (2006)

  7. No Access

    Article

    Biophysical studies on the differentiation of human CD14+ monocytes into dendritic cells

    Dendritic cells (DCs), which are the most efficient antigen-presenting cells (APCs) currently known, can be derived from CD14+ monocytes (DC predecessor cells) in vitro. Immature DCs actively take up antigens and...

    Zhu Zeng, **ao Liu, Yuhui Jiang, Guotao Wang, Jun Zhan… in Cell Biochemistry and Biophysics (2006)

  8. No Access

    Article

    TFAR19 gene changes the biophysical properties of murine erythroleukemia cells

    TFAR19 is a novel apoptosis-related gene and can accelerate cell apoptosis in the presence of apoptosis inducements. Here, we studied the effects of TFAR19 on some biophysical properties of mouse erythroleukem...

    Li Gu, Yuhui Jiang, Ying Wang, Weijuan Yao, Dagong Sun… in Cell Biochemistry and Biophysics (2005)

  9. No Access

    Article

    Effects of TFAR19 gene on the growth and biorheological properties of mouse erythroleukemia cell line MEL

    Using the method of gene transfection with liposome, we obtained the mouse erythroleukemia cell line MEL-TF19, which stably carries TFAR19, a novel apoptosis-related gene. The expression of TFAR19 was detected by...

    Li Gu, Weijuan Yao, Zongyi Yan, Lide **e… in Science in China Series C: Life Sciences (2003)

  10. No Access

    Article

    Microrheological characteristics of reticulocyte in vivo

    Using the method of phenylhydrazine-induced anemia in rabbits, a mass of new reticulocytes, which synchronously grow, were got in vivo. The measurements of deformation index, orientation index, electrophoresis mo...

    Lide **e, Dagong Sun, Weijuan Yao, Zongyao Wen in Science in China Series C: Life Sciences (2002)

  11. No Access

    Article

    Biophysical and biorheological studies on the precursor cells at different stages

    Splenic erythroblasts were obtained from mice during the acute disease caused by anemiainducing virus (FVA). They were cultured in a medium containing EPO, BSA and so on. We studied their biomechanical and hem...

    **hua Wang, Dagong Sun, Weijuan Yao, Zhu Zeng… in Science in China Series C: Life Sciences (2002)

  12. No Access

    Article

    Biophysical meanings of orientation and deformation of RBCs in shear flow field of low viscosity with new Ektacytometry

    The rheological behavior of RBCs treated with WGA of different concentrations was measured by the recently developed new Ektacytometry method in suspending medium of low viscosity. The biophysical meanings of ...

    Zongyao Wen, Tie Gao, Zongyi Yan, Lichuan Song… in Science in China Series C: Life Sciences (1998)