100 Result(s)
within
Life Sciences
Biomaterials
Biotechnology
Regenerative Medicine/Tissue Engineering
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Chapter
Research into the Cellular and Molecular Mechanisms of Regeneration in Salamanders: Then and Now
Urodele amphibians are unrivalled in their ability to regenerate as adults and provide a unique template in which to study the faithful repair of tissues and organs in tetrapods. They display a robust capacity...
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Dependency on Non-myogenic Cells for Regeneration of Skeletal Muscle
Humans and other vertebrates have evolved a robust repair mechanism required to respond to overuse, trauma, and disease. In amphibians, some reptiles and fish, entire muscles can be regenerated in response to ...
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Digit Regeneration in Mammals
The astonishing regenerative ability of the urodele amphibian limb has long been investigated as the chief model for regeneration in vertebrates. The urodele limb responds to amputation via a process called ep...
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Regenerative Strategies for the Central Nervous System
Injury or disease to the central nervous system may result in substantial debilitating consequences for the effected patient. Current clinical treatments fall short of directly addressing the disease/injury pa...
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Regeneration: Lessons from the Lizard
While regeneration of appendages is observed in a number of vertebrates, including teleost fish, amphibians, and squamate reptiles, birds and mammals, including humans, have very limited capacity. The combinat...
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Cartilage Healing, Repair, and Regeneration: Natural History to Current Therapies
Osteoarthritis (OA), the most prevalent form of arthritis, affects up to 15 % of the adult population and is principally characterized by degeneration of the articular cartilage component of the joint. While v...
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Cellular Approaches to Adult Mammalian Heart Regeneration
Adult mammalian hearts lack significant regenerative potential, partially explaining why cardiomyopathies are a major cause of human death in the world. By contrast, adult lower vertebrates and neonatal mice c...
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Emerging Trends in the Applications of Metallic and Ceramic Biomaterials
This chapter discusses the different types of biomaterials used for medical applications. Metallic, ceramic, and nanomaterial-based biomaterials are classified and described based on their physical and biocomp...
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Silk-Based Materials and Composites: Fabrication and Biomedical Applications
In modern manufacturing, natural materials represent a powerful template for creating multifunctional structures in a sustainable and eco-friendly way. In addition, biological systems that have evolved against...
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3D Topological Scanning and Multi-material Additive Manufacturing for Facial Prosthesis Development
Prosthetic-based rehabilitation is an alternative to and offers several advantages over surgical intervention. Prosthetic devices are commonly handmade, requiring significant amounts of skilled labour and subj...
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Engineering Natural-Based Photocrosslinkable Hydrogels for Cartilage Applications
Articular tissue is an avascular tissue at the ends of articulating joints which provides lubrication and transmission of compressive forces during movement. The tissue has poor regenerative capacity and low c...
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Bioglasses for Bone Tissue Engineering
The field of bone tissue engineering, which is rapidly evolving, aims at the regeneration of the bone structure and its functions. In regenerative medicine, the use of 3D porous structures aims to mimic the bo...
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Emerging Trends in Polymers, Composites, and Nano Biomaterial Applications
This chapter introduces synthetic polymers, carbon-based composites, and carbon nanotube-based biomaterials. The implementation of hydrogels for drug delivery carriers and tissue engineering applications is di...
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Materials Properties and Manufacturing Processes of Nitinol Endovascular Devices
Both shape memory alloy and superelastic properties of nitinol material have attracted substantial attentions in a wide range of medical applications, specifically endovascular devices. The device could be col...
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Medical Applications of Additive Manufacturing
Rapid advances in imaging and additive manufacturing (AM) technologies are significantly changing clinical practice. Additive manufacturing, with its flexibility, provides a highly customizable and patient-spe...
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Exoskeletons for Lower Limb Applications: A Review
Exoskeletons are assistive devices that play a significant role in the lives of people who have partially or completely lost the functions of their limbs. These robotic devices can be used in rehabilitation, a...
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Nanoparticles for Tissue Engineering: Type, Properties, and Characterization
The multidisciplinary area of tissue engineering unifies various fields such as medical biology, engineering, and material science that focus on develo** biological alternatives to increase the functions of ...
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Application of Nanoparticles in Soft Tissue Engineering
Tissue engineering is an interdisciplinary approach that integrates several fields of study such as biology, biochemistry, chemistry, nanotechnology, engineering, and material science. Three components are com...
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Biomimetic via Exosome Mimetics in Regenerative Medicine and Therapeutics
Over the years, the field of regenerative medicine and therapeutics has witnessed several modifications in terms of the delivery vehicle used and their complex engineering to achieve the targeted drug/cargo de...
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Strategies to Improve Delivery of Bioactive Agents
The delivery of bioactive agents/drugs in disease therapy and its improper disposal is one of the major causes of the constant rise in pollution levels. The majority of these factors depend upon alternative ap...
