6 Result(s)

Article

SARS-CoV-2 variants of concern are emerging in India

Jasdeep Singh, Syed Asad Rahman, Nasreen Z. Ehtesham, Subhash Hira… in Nature Medicine (2021)

Article

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance

Pooled CRISPR–Cas9 knock out screens provide a valuable addition to the methods available for novel drug target identification and validation. However, where gene editing is targeted to amplified loci, the res...

Carlos le Sage, Steffen Lawo, Prince Panicker, Tim M. E. Scales… in Scientific Reports (2017)

Article

Small Molecule Subgraph Detector (SMSD) toolkit

Finding one small molecule (query) in a large target library is a challenging task in computational chemistry. Although several heuristic approaches are available using fragment-based chemical similarity searc...

Syed Asad Rahman, Matthew Bashton, Gemma L Holliday… in Journal of Cheminformatics (2009)

Article

Genomes of Helicobacter pylori from native Peruvians suggest admixture of ancestral and modern lineages and reveal a western type cag-pathogenicity island

Helicobacter pylori is presumed to be co-evolved with its human host and is a highly diverse gastric pathogen at genetic levels. Ancient origins of H. pylori in the New World are still debatable. It is not clear ...

S Manjulata Devi, Irshad Ahmed, Aleem A Khan, Syed Asad Rahman, Ayesha Alvi… in BMC Genomics (2006)

Article

Metabolic Network Analysis: Implication And Application

Syed Asad Rahman, Pardha Saradhi Jonnalagadda, Jyothi Padiadpu… in BMC Bioinformatics (2005)