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Article
Mitochondrial phylogeography of the genus Eremophila confirms underestimated species diversity in the Palearctic
Phylogeographic analyses of the genus Eremophila (Horned Lark E. alpestris and Temminck’s Lark E. bilopha) were carried out based on the mitochondrial cytochrome b and ND2 genes. Four primary lineages with para-/...
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Article
Genetic and biometric variation across the fragmented range of Jerdon’s Babbler, Chrysomma altirostre, a threatened Oriental grassland specialist
Jerdon’s Babbler Chrysomma altirostre is a threatened Oriental grassland specialist passerine heavily affected by habitat loss. Its now-relictual range spans from Pakistan to Myanmar covering three poorly-studied...
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Article
Open AccessPhylogeography of the smooth-coated otter (Lutrogale perspicillata): distinct evolutionary lineages and hybridization with the Asian small-clawed otter (Aonyx cinereus)
We investigated the phylogeography of the smooth-coated otter (Lutrogale perspicillata) to determine its spatial genetic structure for aiding an adaptive conservation management of the species. Fifty-eight modern...
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Article
Genetic Polymorphisms of X-ray Repair Cross-Complementing Group 1 and Apurinic/Apyrimidinic Endonuclease-1 in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a heterogeneous collection of conditions characterized by irreversible expiratory airflow limitation. The disease is interspersed with exacerbations; periods of ...
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Article
Functional polymorphisms in XRCC-1 and APE-1 contribute to increased apoptosis and risk of ulcerative colitis
The present study was designed to investigate the role of X-ray cross-complementing group 1 (XRCC1) and apurinic/apyrimidinic endonuclease 1 (APE1) polymorphisms in apoptosis and the risk of ulcerative colitis (U...
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Gastrointestinal Stem Cells
Stem cell research is advancing at an incredible pace, with new discoveries and clinical applications being reported from all over the world. Stem cells are functionally defined by their ability to self-renew...
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Article
Relevance of Helicobacter pylori genotypes in gastric pathology and its association with plasma malondialdehyde and nitric oxide levels
Persistent infection with Helicobacter pylori confers an increased risk of peptic ulceration and gastric adenocarcinoma. Reactive oxygen and nitrogen species play a crucial role in the progression from normal gas...
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Article
Human-mediated introgression of exotic chukar (Alectoris chukar, Galliformes) genes from East Asia into native Mediterranean partridges
Mediterranean red-legged (Alectoris rufa) and rock (Alectoris graeca) partridge populations are affected by genetic pollution. The chukar partridge (Alectoris chukar), a species only partly native to Europe, is t...
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Article
Genetic insight into Mediterranean chukar (Alectoris chukar, Galliformes) populations inferred from mitochondrial DNA and RAPD markers
The chukar (Alectoris chukar, Galliformes) is one of the most important game birds as it is widely distributed and hunted over the whole of its range. The aim of this work was to assess the genetic differentiatio...
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Article
Open AccessGenomes of Helicobacter pylori from native Peruvians suggest admixture of ancestral and modern lineages and reveal a western type cag-pathogenicity island
Helicobacter pylori is presumed to be co-evolved with its human host and is a highly diverse gastric pathogen at genetic levels. Ancient origins of H. pylori in the New World are still debatable. It is not clear ...
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Article
Open AccessAntimicrobial activities of Eugenol and Cinnamaldehyde against the human gastric pathogen Helicobacter pylori
Eradication of Helicobacter pylori is an important objective in overcoming gastric diseases. Many regimens are currently available but none of them could achieve 100% success in eradication. Eugenol and cinnamald...
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Article
Open AccessComparative genomics of Helicobacter pylori isolates recovered from ulcer disease patients in England
Genomic diversity of H. pylori from many different human populations is largely unknown. We compared genomes of 65 H. pylori strains from Nottingham, England. Molecular analysis was carried out to identify rearra...
