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Open AccessRepeating the errors of the past: the hazards of a commercial human milk industry
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Open AccessCorrection: Improving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group
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The future of perinatal research
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Open AccessImproving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group
The COVID-19 pandemic has had a devastating impact on multiple aspects of healthcare, but has also triggered new ways of working, stimulated novel approaches in clinical research and reinforced the value of pr...
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Evaluating preterm care across Europe using the eNewborn European Network database
The inefficiency of recording data repeatedly limits the number of studies conducted. Here we illustrate the wider use of data captured as part of the European eNewborn benchmarking programme.
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Clinical and molecular evidence of accelerated ageing following very preterm birth
The mechanisms responsible for the associations between very preterm birth and a higher risk of poor cardiovascular and metabolic health in adult life are unknown.
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Parent, child and public involvement in child health research: core value not just an optional extra
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Develo** core outcome set for women’s, newborn, and child health: the CROWN Initiative
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The future of pediatric research: European perspective
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Open AccessThe International Network for Evaluating Outcomes of very low birth weight, very preterm neonates (iNeo): a protocol for collaborative comparisons of international health services for quality improvement in neonatal care
The International Network for Evaluating Outcomes in Neonates (iNeo) is a collaboration of population-based national neonatal networks including Australia and New Zealand, Canada, Israel, Japan, Spain, Sweden,...
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Open AccessPreterm birth–associated neurodevelopmental impairment estimates at regional and global levels for 2010
In 2010, there were an estimated 15 million preterm births worldwide (<37 wk gestation). Survivors are at risk of adverse outcomes, and burden estimation at global and regional levels is critical for priority ...
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Aberrant Adiposity and Ectopic Lipid Deposition Characterize the Adult Phenotype of the Preterm Infant
Our investigation addresses the hypothesis that disruption of third trimester development by preterm birth alters multiple biological pathways affecting metabolic health in adult life. We compared healthy adul...
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The Influence of Maternal Body Mass Index on Infant Adiposity and Hepatic Lipid Content
Maternal overweight and obesity are associated with adverse offspring outcome in later life. The causal biological effectors are uncertain. Postulating that initiating events may be alterations to infant body ...
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A Randomized, Double-Blind, Controlled Trial of the Effect of Prebiotic Oligosaccharides on Enteral Tolerance in Preterm Infants (ISRCTN77444690)
Breast milk prebiotic oligosaccharides are believed to promote enteral tolerance. Many mothers delivering preterm are unable to provide sufficient milk. We conducted a multicenter, randomized, controlled trial...
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Whole Body Magnetic Resonance Imaging of Healthy Newborn Infants Demonstrates Increased Central Adiposity in Asian Indians
Abdominal adiposity and metabolic ill health in Asian Indians are a growing public health concern. Causal pathways are unknown. Preventive measures in adults have had limited success. The aim of this observati...
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Determinants of Adiposity during Preweaning Postnatal Growth in Appropriately Grown and Growth-Restricted Term Infants
The distribution and quantity of adipose tissue are markers of morbidity risk in children and adults. Poor intrauterine growth and accelerated postnatal growth are believed to add to these risks. The aim of th...
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Glucocorticoid Exposure in Preterm Babies Predicts Saliva Cortisol Response to Immunization at 4 Months
Preterm babies are exposed to multiple stressors and this may have long-term effects. In particular, high levels of endogenous cortisol might have a programming effect on the hypothalamic-pituitary-adrenal axi...
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Altered Adiposity after Extremely Preterm Birth
The quantity and distribution of adipose tissue are markers of morbidity risk. The third trimester of human development is a period of rapid adipose tissue deposition. Preterm infants may be at risk of altered...
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Distribution of Adipose Tissue in the Newborn
Regional differences in adipose tissue distribution are associated with differences in adipocyte metabolism and obesity-related morbidities. Intrauterine growth restriction appears to place individuals at grea...
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The Effects of Repeated Antenatal Glucocorticoid Therapy on the Develo** Brain
Antenatal glucocorticoid (GC) therapy improves infant outcome following preterm birth. As approximately 50% of women given a first course of antenatal GCs remain undelivered 7-14 d later, many clinicians admin...