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Article
Association of low hemoglobin at birth and neurodevelopmental outcomes in preterm neonates ≤28 weeks’ gestation: a retrospective cohort study
To compare neurodevelopmental outcomes at 18–24 months corrected age (CA) for preterm infants who had hemoglobin levels <120 g/l versus those with hemoglobin level ≥120 g/l at birth.
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Open AccessTranslating regenerative medicine therapies in neonatal necrotizing enterocolitis
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Open AccessDoes the use of higher versus lower oxygen concentration improve neurodevelopmental outcomes at 18–24 months in very low birthweight infants?
Immediately after birth, the oxygen saturation is between 30 and 50%, which then increases to 85–95% within the first 10 min. Over the last 10 years, recommendations regarding the ideal level of the initial fr...
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Article
Efficacy and safety of dexmedetomidine for analgesia and sedation in neonates: a systematic review
Opioids and benzodiazepines have historically been employed for pain relief; however, they are associated with detrimental long-term neurodevelopmental consequences. Dexmedetomidine, a highly selective alpha-2...
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Article
Epidemiology of post-hemorrhagic ventricular dilatation in very preterm infants
To describe the incidence, trends, management’s variability and short-term outcomes of preterm infants with severe post-hemorrhagic ventricular dilatation (sPHVD).
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Article
Outcomes of infants with hypoxic-ischemic encephalopathy during COVID-19 pandemic lockdown in Canada: a cohort study
To evaluate change in the severity of hypoxic-ischemic encephalopathy (HIE) and associated morbidities between pre- and during COVID-19 pandemic periods in Canada.
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Article
Clinical burden associated with therapies for cardio-pulmonary critical decompensation in preterm neonates across Canadian neonatal intensive care units
The aim of this retrospective cohort study was to study the clinical burden associated with cardio-pulmonary critical decompensations (CPCDs) in preterm neonates and factors associated with mortality. Through ...
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Article
Antimicrobial utilization in very-low-birth-weight infants: association with probiotic use
To examine the association between probiotic use and antimicrobial utilization.
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Article
Variations in practices and outcomes of neonates with hypoxic ischemic encephalopathy treated with therapeutic hypothermia across tertiary NICUs in Canada
To characterize variations in practices and outcomes for neonates with hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH) across Canadian tertiary Neonatal Intensive Care Units (NI...
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Article
A practical approach toward interpretation of amplitude integrated electroencephalography in preterm infants
The develo** preterm brain is vulnerable to injury, especially during periods of clinical instability; therefore, monitoring the brain may provide important information on brain health. Over the last 2 decad...
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Article
Remote ischemic conditioning in necrotizing enterocolitis: study protocol of a multi-center phase II feasibility randomized controlled trial
Remote ischemic conditioning (RIC) is a maneuver involving brief cycles of ischemia reperfusion in an individual’s limb. In the early stage of experimental NEC, RIC decreased intestinal injury and prolonged su...
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Article
Poractant alfa versus bovine lipid extract surfactant: prospective comparative effectiveness study
To compare short term respiratory outcomes in preterm infants treated with bovine lipid extract surfactant or poractant alfa.
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Article
Open AccessAdapting obstetric and neonatal services during the COVID-19 pandemic: a sco** review
The provision of care to pregnant persons and neonates must continue through pandemics. To maintain quality of care, while minimizing physical contact during the Severe Acute Respiratory Syndrome-related Coron...
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Article
Association of timing of birth with mortality among preterm infants born in Canada
To assess the association between time of birth and mortality among preterm infants.
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Article
Maternal age and long-term neurodevelopmental outcomes of preterm infants < 29 weeks gestational age
The objective of this study is to assess the impact of maternal age on neurodevelopmental (ND) outcomes of infants < 29 weeks gestational age (GA) at 18–24 months.
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Article
Neurodevelopmental outcomes of singleton large for gestational age infants <29 weeks’ gestation: a retrospective cohort study
To compare neurodevelopmental outcomes of large and appropriate for gestational age (LGA, AGA) infants <29 weeks’ gestation at 18–24 months of corrected age.
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Article
Steroids for the Management of Neonates With Meconium Aspiration Syndrome: A Systematic Review and Meta-analysis
Steroids are a potential treatment for pulmonary inflammation in meconium aspiration syndrome (MAS).
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Article
A holistic approach to infant growth assessment considers clinical, social and genetic factors rather than an assessment of weight at a set timepoint
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Characteristics and outcomes of preterm neonates according to number of doses of surfactant received
To identify characteristics and outcomes of infants who received multiple doses of surfactant vs those who received one dose or none.
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Article
Fish oil-containing multicomponent lipid emulsion vs soy-based lipid emulsion and neurodevelopmental outcomes of children born < 29 weeks’ gestation
To compare neurodevelopmental outcomes of extremely preterm children who received soy-medium chain triglycerides-olive-fish oil-containing lipid emulsion (SMOF-LE) vs soy-based LE.