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Open AccessRepeating the errors of the past: the hazards of a commercial human milk industry
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Open AccessCorrection: Improving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group
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Open AccessDevelopment of an international core outcome set for treatment trials in necrotizing enterocolitis—a study protocol
Necrotizing enterocolitis (NEC) is the most lethal disease of the gastrointestinal tract of preterm infants. New and existing management strategies need clinical evaluation. Large heterogeneity exists in the s...
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Open AccessHow to reach agreement: the impact of different analytical approaches to Delphi process results in core outcomes set development
Core outcomes sets are increasingly used to define research outcomes that are most important for a condition. Different consensus methods are used in the development of core outcomes sets; the most common is t...
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The future of perinatal research
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Open AccessImproving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group
The COVID-19 pandemic has had a devastating impact on multiple aspects of healthcare, but has also triggered new ways of working, stimulated novel approaches in clinical research and reinforced the value of pr...
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A View from Paediatric Medicine: Competence, Best Interests, and Operational Pragmatism
The place of children in society, the contributions they make, and their rights and legal status have evolved over time and across countries. Paediatric medical practice, a relatively new specialty, has also e...
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Open AccessIdentification of variation in nutritional practice in neonatal units in England and association with clinical outcomes using agnostic machine learning
We used agnostic, unsupervised machine learning to cluster a large clinical database of information on infants admitted to neonatal units in England. Our aim was to obtain insights into nutritional practice, a...
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Evaluating preterm care across Europe using the eNewborn European Network database
The inefficiency of recording data repeatedly limits the number of studies conducted. Here we illustrate the wider use of data captured as part of the European eNewborn benchmarking programme.
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Clinical and molecular evidence of accelerated ageing following very preterm birth
The mechanisms responsible for the associations between very preterm birth and a higher risk of poor cardiovascular and metabolic health in adult life are unknown.
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Living Reference Work Entry In depth
Global Pandemics, the Mother and Her Infant: Learning from the Past to Help the Future
A pandemic is the worldwide spread of a new disease. The impact of a new infection is unpredictable and potentially devastating because of the lack of preexisting immunity and the great variability in the effe...
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Open AccessA systematic review identifying common data items in neonatal trials and assessing their completeness in routinely recorded United Kingdom national neonatal data
We aimed to test whether a common set of key data items reported across high-impact neonatal clinical trials could be identified, and to quantify their completeness in routinely recorded United Kingdom neonata...
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Parent, child and public involvement in child health research: core value not just an optional extra
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Develo** core outcome set for women’s, newborn, and child health: the CROWN Initiative
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Open AccessA methodological framework for assessing agreement between cost-effectiveness outcomes estimated using alternative sources of data on treatment costs and effects for trial-based economic evaluations
A new methodological framework for assessing agreement between cost-effectiveness endpoints generated using alternative sources of data on treatment costs and effects for trial-based economic evaluations is pr...
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The future of pediatric research: European perspective
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Open AccessThe International Network for Evaluating Outcomes of very low birth weight, very preterm neonates (iNeo): a protocol for collaborative comparisons of international health services for quality improvement in neonatal care
The International Network for Evaluating Outcomes in Neonates (iNeo) is a collaboration of population-based national neonatal networks including Australia and New Zealand, Canada, Israel, Japan, Spain, Sweden,...
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Open AccessPreterm birth–associated neurodevelopmental impairment estimates at regional and global levels for 2010
In 2010, there were an estimated 15 million preterm births worldwide (<37 wk gestation). Survivors are at risk of adverse outcomes, and burden estimation at global and regional levels is critical for priority ...
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Aberrant Adiposity and Ectopic Lipid Deposition Characterize the Adult Phenotype of the Preterm Infant
Our investigation addresses the hypothesis that disruption of third trimester development by preterm birth alters multiple biological pathways affecting metabolic health in adult life. We compared healthy adul...
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The Influence of Maternal Body Mass Index on Infant Adiposity and Hepatic Lipid Content
Maternal overweight and obesity are associated with adverse offspring outcome in later life. The causal biological effectors are uncertain. Postulating that initiating events may be alterations to infant body ...
