65 Result(s)

Article

Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine

Antimicrobial peptides (AMPs), ancient scavengers of bacteria, are very poorly induced in macrophages infected by Mycobacterium tuberculosis (M. tuberculosis), but the underlying mechanism remains unknown. Here, ...

Cheng Peng, Yuanna Cheng, Mingtong Ma, Qiu Chen, Yongjia Duan… in Nature Communications (2024)

Article

Anti-friction gold-based stretchable electronics enabled by interfacial diffusion-induced cohesion

Stretchable electronics that prevalently adopt chemically inert metals as sensing layers and interconnect wires have enabled high-fidelity signal acquisition for on-skin applications. However, the weak interfa...

Jie Cao, Xusheng Liu, Jie Qiu, Zhifei Yue, Yang Li, Qian Xu… in Nature Communications (2024)

Article

Exploring the mechanism and phytochemicals in Psoraleae Fructus-induced hepatotoxicity based on RNA-seq, in vitro screening and molecular docking

Psoraleae Fructus (PF) is a widely-used herb with diverse pharmacological activities, while its related hepatic injuries have aroused public concerns. In this work, a systematic approach based on RNA sequencin...

Huiying Shang, **an Liu, **chao Pan, Hongbo Cheng, Zengchun Ma… in Scientific Reports (2024)

Article

Analysis of factors associated with delayed diagnosis and treatment of testicular torsion in 1005 cases from Chongqing city, China: a cross-sectional study

This study aimed to investigate the clinical and social factors of delayed treatment for testicular torsion (TT) and to explore the risk factors of testicular excision in China. The clinical data of 1005 patie...

Hongmei Yi, Delin Wang, **aohou Wu, **angzhi Gan, Dan Wang, **n zhao… in Scientific Reports (2023)

Article

Inhibition of chitin deacetylases to attenuate plant fungal diseases

Phytopathogenic fungi secrete chitin deacetylase (CDA) to escape the host’s immunological defense during infection. Here, we showed that the deacetylation activity of CDA toward chitin is essential for fungal ...

Lin Liu, Yeqiang **a, Yingchen Li, Yong Zhou, **aofeng Su… in Nature Communications (2023)

Article

Mechanical metamaterials made of freestanding quasi-BCC nanolattices of gold and copper with ultra-high energy absorption capacity

Nanolattices exhibit attractive mechanical properties such as high strength, high specific strength, and high energy absorption. However, at present, such materials cannot achieve effective fusion of the above...

Hongwei Cheng, **aoxia Zhu, **aowei Cheng, Pengzhan Cai, Jie Liu… in Nature Communications (2023)

Article

Unintended consequences of combating desertification in China

Since the early 2000s, China has carried out extensive “grain-for-green” and grazing exclusion practices to combat desertification in the desertification-prone region (DPR). However, the environmental and soci...

Xunming Wang, Quansheng Ge, **n Geng, Zhaosheng Wang, Lei Gao… in Nature Communications (2023)

Article

The classical pathway triggers pathogenic complement activation in membranous nephropathy

Membranous nephropathy (MN) is an antibody-mediated autoimmune disease characterized by glomerular immune complexes containing complement components. However, both the initiation pathways and the pathogenic si...

Larissa Seifert, Gunther Zahner, Catherine Meyer-Schwesinger… in Nature Communications (2023)

Article

Author Correction: BTLA suppress acute rejection via regulating TCR downstream signals and cytokines production in kidney transplantation and prolonged allografts survival

Jiayi Zhang, Hengcheng Zhang, Zijie Wang, Haiwei Yang, Hao Chen… in Scientific Reports (2022)

Article

People’s perceptions and experience of managing life after recurrent pancreatitis: a qualitative study in eastern China

There is a high rate of recurrent hypertriglyceridemic acute pancreatitis (HTG-RAP) and risk of develo** into chronic pancreatitis among recurrent hypertriglyceridemic acute pancreatitis. The key to avoiding...

Lin Chen, **ngxing Zhou, **amin Tu, Hongmei Cheng, Zhaotao Duan… in Scientific Reports (2022)

Article

Quantitative investigation on the heterogeneity of deformation fields in sandstone pre-existing cracks during damage evolution

The inherently heterogeneous microstructures of rocks lead to heterogeneity of the deformation distribution within the rock volume. In this study, experiments were conducted on red sandstone specimens with fou...

Hongming Cheng, **aobin Yang, Yanyu Pei, Yimin Song in Scientific Reports (2022)

Article

A quantitative study on the impact of working environment on the well-being of teachers in China’s private colleges

Teacher well-being is a prominent issue in policy and public debates. Those teachers working in private schools deserve concern given concerns about their working environment. Focus of this study: to learn abo...

**** Chen, Hongyan Cheng, Dan Zhao, Fuyu Zhou, Yuan Chen in Scientific Reports (2022)

Article

A case of antiferrochirality in a liquid crystal phase of counter-rotating staircases

Helical structures continue to inspire, prompted by examples such as DNA double-helix and alpha-helix in proteins. Most synthetic polymers also crystallize as helices, which relieves steric clashes by twisting...

Ya-xin Li, Hong-fei Gao, Rui-bin Zhang, Kutlwano Gabana… in Nature Communications (2022)

Article

Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages

Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S-glutathionylation plays an important role in cellular antioxidant defense. Here we report that the expression of deglutathionyla...

Yuxian Guo, Yaru Liu, Shihao Zhao, Wangting Xu, Yiqing Li… in Nature Communications (2021)

Article

Performance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth

There is no consistent conclusion on which adiposity measure is best to predict cardiovascular risk factors in youth. The present study aims to assess the performance of body mass index (BMI), waist circumfere...

Hong Cheng, Bo **, Junting Liu, Yinkun Yan, Jie Mi in Scientific Reports (2021)

Article

Endothelial deletion of SHP2 suppresses tumor angiogenesis and promotes vascular normalization

SHP2 mediates the activities of multiple receptor tyrosine kinase signaling and its function in endothelial processes has been explored extensively. However, genetic studies on the role of SHP2 in tumor angiog...

Zhiyong Xu, Chunyi Guo, Qiaoli Ye, Yueli Shi, Yihui Sun, Jie Zhang… in Nature Communications (2021)

Article

Multi-omics profiling of primary small cell carcinoma of the esophagus reveals RB1 disruption and additional molecular subtypes

Primary small cell carcinoma of the esophagus (PSCCE) is a lethal neuroendocrine carcinoma. Previous studies proposed a genetic similarity between PSCCE and esophageal squamous cell carcinoma (ESCC) but provid...

Renda Li, Zhenlin Yang, Fei Shao, Hong Cheng, Yaru Wen, Si** Sun… in Nature Communications (2021)

Article

Autosomal dominant tubulointerstitial kidney disease genotype and phenotype correlation in a Chinese cohort

Genes of UMOD, HNF1B, MUC1, REN and SEC61A1 were reported to be associated with autosomal dominant tubulointerstitial kidney disease (ADTKD). 48 probands and their family members (N = 27) were enrolled in this ge...

Kun**g Gong, Min **a, Yaqin Wang, Na Wang, Ying Liu… in Scientific Reports (2021)

Article

Variation of rhizosphere microbial community in continuous mono-maize seed production

Soil microbe is crucial to a healthy soil, therefore its diversities and abundances under different conditions are still need fully understand.The aims of the study were to characterize the community structure...

Yunchen Zhao, Wenjiang Fu, Changwei Hu, Guangquan Chen, Zhanwen **ao… in Scientific Reports (2021)

Article

Efficient Synchronous Extraction of Nickel, Copper, and Cobalt from Low–Nickel Matte by Sulfation Roasting‒Water Leaching Process

Considering that the low recovery efficiency and the massive loss of valuable metals by the traditional pyrometallurgical process smelting low‒nickel matte. Therefore, this paper focuses on studying the optima...

Qiangchao Sun, Hongwei Cheng, **aoyong Mei, Yanbo Liu, Guangshi Li… in Scientific Reports (2020)