4 Result(s)

Article

Publisher Correction: Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis

Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert… in Nature Communications (2023)

Article

Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis

Little is known about the mechanistic significance of the ubiquitin proteasome system (UPS) in a kidney autoimmune environment. In membranous nephropathy (MN), autoantibodies target podocytes of the glomerular...

Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert… in Nature Communications (2023)

Article

The classical pathway triggers pathogenic complement activation in membranous nephropathy

Membranous nephropathy (MN) is an antibody-mediated autoimmune disease characterized by glomerular immune complexes containing complement components. However, both the initiation pathways and the pathogenic si...

Larissa Seifert, Gunther Zahner, Catherine Meyer-Schwesinger… in Nature Communications (2023)

Article

Enhanced expression of selenocysteine lyase in acute glomerulonephritis and its regulation by AP-1

Acute glomerulonephritis can lead to chronic glomerulonephritis or resolve without permanent damage to the kidneys. Differential gene expression was studied in a model of acute and chronic glomerulonephritis t...

Claudia Jafari, Ulf Panzer, Oliver M. Steinmetz… in Cellular & Molecular Biology Letters (2006)