3 Result(s)

Article

The classical pathway triggers pathogenic complement activation in membranous nephropathy

Membranous nephropathy (MN) is an antibody-mediated autoimmune disease characterized by glomerular immune complexes containing complement components. However, both the initiation pathways and the pathogenic si...

Larissa Seifert, Gunther Zahner, Catherine Meyer-Schwesinger… in Nature Communications (2023)

Article

Correction to: Increased biosynthesis of acetyl-CoA in the yeast Saccharomyces cerevisiae by overexpression of a deregulated pantothenate kinase gene and engineering of the coenzyme A biosynthetic pathway

Judith Olzhausen, Mathias Grigat, Larissa Seifert… in Applied Microbiology and Biotechnology (2022)

Article

Increased biosynthesis of acetyl-CoA in the yeast Saccharomyces cerevisiae by overexpression of a deregulated pantothenate kinase gene and engineering of the coenzyme A biosynthetic pathway

Coenzyme A (CoA) and its derivatives such as acetyl-CoA are essential metabolites for several biosynthetic reactions. In the yeast S. cerevisiae, five enzymes (encoded by essential genes CAB1-CAB5; coenzyme A bio...

Judith Olzhausen, Mathias Grigat, Larissa Seifert… in Applied Microbiology and Biotechnology (2021)