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Article

Endothelial deletion of SHP2 suppresses tumor angiogenesis and promotes vascular normalization

SHP2 mediates the activities of multiple receptor tyrosine kinase signaling and its function in endothelial processes has been explored extensively. However, genetic studies on the role of SHP2 in tumor angiog...

Zhiyong Xu, Chunyi Guo, Qiaoli Ye, Yueli Shi, Yihui Sun, Jie Zhang… in Nature Communications (2021)