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Article
Prevalence of hypertension and its associations with body composition across Chinese and American children and adolescents
The age of onset of hypertension (HTN) is decreasing, and obesity is a significant risk factor. The prevalence and racial disparities in pediatric HTN and the association between body composition and blood pre...
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Article
Occupational exposure to silica and risk of gastrointestinal cancers: a systematic review and meta-analysis of cohort studies
Although silica is a proven lung carcinogen, there is no convincing evidence linking crystalline silica to gastrointestinal malignancies.
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Article
A hybrid iterative Fourier ptychographic microscopy algorithm based on fusion of random phase perturbation and gradient descent strategy
Fourier ptychographic microscopy (FPM) incorporates the phase recovery and synthetic aperture to achieve large field of view, high resolution, and large spatial bandwidth product with quantitative phase imagin...
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Article
Cross-sectional and Longitudinal Associations Between Metal Mixtures and Serum C3, C4: Result from the Manganese‑exposed Workers Healthy Cohort
Exposure to metal mixtures compromises the immune system, with the complement system connecting innate and adaptive immunity. Herein, we sought to explore the relationships between blood cell metal mixtures an...
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Article
Open AccessRoxadustat and Oral Iron Absorption in Chinese Patients with Anemia of Chronic Kidney Disease: A Randomized, Open-Label, Phase 4 Study (ALTAI)
Anemia of chronic kidney disease (CKD) has a high incidence and is associated with many disease conditions. Iron dysmetabolism is an important contributor to anemia in CKD patients.
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Article
Anti-CD20 treatment attenuates Th2 cell responses: implications for the role of lung follicular mature B cells in the asthmatic mice
B cells were believed to act as antigen-presenting cells (APCs) to promote T helper type 2 (Th2) cell responses. However, the role of lung B cells and its subpopulations in Th2 cell responses in asthma remains...
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Article
Open AccessReminiscent music therapy combined with robot-assisted rehabilitation for elderly stroke patients: a pilot study
Although some studies suggest that robot-assisted technology can significantly improve upper limb function in stroke patients compared to traditional rehabilitation training, it is still necessary to incorpora...
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Article
Open AccessA qualitative study of the factors impacting implementation of the national action plan to contain antimicrobial resistance (2016–2020) in medical institutions
Antimicrobial resistance (AMR) has emerged as a serious global public health crisis. In response, 2016, 14 ministries in China, under the leadership of the National Health Commission, collaboratively issued th...
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Article
Open AccessBased on whole-exome sequencing to explore the rule of Herceptin and TKI resistance in breast cancer patients
Breast cancer is the second leading cause of cancer-related death in women, and drug resistance during treatment is a major challenge. However, the mechanisms underlying drug resistance are not fully understoo...
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Article
Correction to: Prevalence of hypertension and its associations with body composition across Chinese and American children and adolescents
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Chapter and Conference Paper
Analysis of Bandgap Formation Mechanism Based on the Programmable Curved-Beam Periodic Structure
In order to investigate the propagation and isolation mechanisms of elastic waves, we propose a programmable curved beam periodic structure (PCBPS). The PCBPS is assembled by a unit cell containing bistable cu...
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Article
Open AccessGenetic insights into the association of statin and newer nonstatin drug target genes with human longevity: a Mendelian randomization analysis
It remains controversial whether the long-term use of statins or newer nonstatin drugs has a positive effect on human longevity. Therefore, this study aimed to investigate the genetic associations between diff...
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Article
Open AccessSpinal apolipoprotein E is involved in inflammatory pain via regulating lipid metabolism and glial activation in the spinal dorsal horn
Inflammation and nerve injury promote astrocyte activation, which regulates the development and resolution of pain, in the spinal dorsal horn. APOE regulates lipid metabolism and is predominantly expressed in ...
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Article
Correction: Microglial Depletion does not Affect the Laterality of Mechanical Allodynia in Mice
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Article
Open AccessPIK3CD correlates with prognosis, epithelial–mesenchymal transition and tumor immune infiltration in breast carcinoma
Breast carcinoma (BRCA) is one of the most common, fatal, and aggressive cancers, with increasing morbidity that has a major impact on human health. PIK3CD appears to have important roles in the beginning and ...
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Article
Associations of metal mixtures with thyroid function and potential interactions with iodine status: results from a cross-sectional study in MEWHC
Few studies are available on associations between metal mixture exposures and disrupted thyroid hormone homeostasis; particularly, the role of iodine status was ignored. Here, we aimed to explore the cross-sec...
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Article
Accelerating massive queries of approximate nearest neighbor search on high-dimensional data
Approximate nearest neighbor (ANN) search on high-dimensional data is a fundamental operation in many applications. In this paper, we study massive queries of ANN (MQ-ANN) search, which deals with a large numb...
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Article
Microglial Depletion does not Affect the Laterality of Mechanical Allodynia in Mice
Mechanical allodynia (MA), including punctate and dynamic forms, is a common and debilitating symptom suffered by millions of chronic pain patients. Some peripheral injuries result in the development of bilate...
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Article
Pharmacokinetics, Pharmacodynamics and Safety of Janagliflozin in Chinese Type 2 Diabetes Mellitus Patients with Renal Impairment
Janagliflozin is a novel sodium–glucose cotransport-2 inhibitor. Despite its remarkable effect in glycemic control, no systematic research has evaluated the effect of renal impairment (RI) on its pharmacokinet...
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Article
The Characterizations on a Class of Weakly Weighted Einstein–Finsler Metrics
In this paper, we mainly introduce and study the weakly weighted Einstein–Finsler metrics. First, we show that weakly weighted Einstein–Kropina metrics must be of isotropic S-curvature with respect to the Buse...
