-
Article
Protein-based nanocarriers for efficient Etoposide delivery and cancer therapy
Etoposide, a DNA damage-inducing agent, is widely used for malignant tumors. However, insufficient solubility, poor bioavailability and adverse events limited the treatment outcomes and prognosis. To address t...
-
Article
Rare-earth Nanomaterials for Potential Brain Disease Theranostics
Brain diseases with high mortality cause severe threats to human health and life. Non-invasively high-resolution imaging technologies contribute to obtaining detailed brain structures to figure out the pathoge...
-
Article
Open AccessCalculation Model for the Steady-State Vibration Amplitude of a New Type of Cascaded Composite Structure-Based Ultrasonic Transducer
The steady-state vibration amplitude is an important performance indicator of high-frequency ultrasonic transducers for ultrasonically assisted manipulating, machining, and manufacturing. This work aimed to de...
-
Article
Tumor microenvironment-responsive modular integrated nanocomposites for magnetically targeted and photothermal enhanced catalytic therapy
Achieving efficient integration of cancer diagnosis and therapy is of great significance to human health, but the construction of a multifunctional intelligent therapy system still faces great challenges. In t...
-
Article
Open AccessGreen synthesis of stable hybrid biocatalyst using a hydrogen-bonded, π-π-stacking supramolecular assembly for electrochemical immunosensor
Rational integration of native enzymes and nanoscaffold is an efficient means to access robust biocatalyst, yet remains on-going challenges due to the trade-off between fragile enzymes and harsh assembling con...
-
Article
Coupling Fe and Mo single atoms on hierarchical N-doped carbon nanotubes enhances electrochemical nitrogen reduction reaction performance
Electrochemical nitrogen reduction reaction (NRR) paves a new way to cost-efficient production of ammonia, but is still challenging in the sluggish kinetics caused by hydrogen evolution reaction competition an...
-
Article
Engineering CeO2/CuO heterostructure anchored on upconversion nanoparticles with boosting ROS generation-primed apoptosis-ferroptosis for cancer dynamic therapy
Highly toxic reactive oxygen species (ROS) induced apoptosis and ferroptosis have been considered as significant cell death pathways for cancer therapy. However, insufficient amount of intracellular ROS extrem...
-
Article
Novel nanocarrier for promoting tumor synergistic therapy by down-regulation of heat shock proteins and increased Fe3+ supply
With the emergence of new therapeutic methods, synergistic therapy has attracted great attention because it can improve the treatment efficacy, and reduce the toxic side effects. Herein, we developed a nanocar...
-
Article
Experimental investigation on erosion progression and strength reduction of gap-graded cohesionless soil subjected to suffusion
Suffusion is a typical mode of internal erosion that leads to the deterioration of earthen structures. A stress-controlled experimental apparatus has been developed, which is adopted to investigate the charact...
-
Article
Diagnostic accuracy of different cross-sectional imaging techniques for disease location and activity in Crohn’s disease and external validation and comparison of MARIAs and IBUS-SAS
The comparative accuracy of cross-sectional imaging techniques for evaluating Crohn’s disease (CD) remains uncertain. This study aimed to assess diagnostic accuracy of disease location and activity in differen...
-
Article
Design, Verification, and Protection Setting of Superconducting Fault Current Limiter for a 10 kV Power Network
The level of fault current increases as urban power grid expands in recent years. The traditional relay protection has difficulties in preventing the increased fault current in power grid. Magneto-biased super...
-
Article
Engineering Mechanical Strong Biomaterials Inspired by Structural Building Blocks in Nature
The intricate multiscale architectures in natural structural building blocks provide many sources of inspiration for the designs of artificial biomaterials. In nature, the assembly of highly ordered molecular c.....
-
Article
Structural and functional imaging of brains
Analyzing the complex structures and functions of brain is the key issue to understanding the physiological and pathological processes. Although neuronal morphology and local distribution of neurons/blood vess...
-
Chapter and Conference Paper
PCB Component Rotation Detection Based on Polarity Identifier Attention
Accurate detection of component rotation is a critical task in the production of printed circuit boards (PCBs). However, with the rapid development of integrated circuits, manually labeling large datasets of a...
-
Article
Digital Cofibration and Digital Lusternik-Schnirelmann Category in the Sense of Subdivision
In this paper, using the notion of subdivision, the authors generalize the definition of cofibration in digital topology and show that this kind of cofibration is injective in the sense of subdivision. Meanwhi...
-
Chapter and Conference Paper
Research of Fault Current Limiting in 66/10 kV Substation with Magneto-Biased Superconducting Fault Current Limiter
Aiming at the short-circuit fault current limiting problem in the power system, the topology of the magneto-biased superconducting fault current limiter is proposed, and the simulation model of the magneto-bia...
-
Article
Effects of fuel injection system and exhaust gas catalytic treatments on PAH emissions from motorcycles
The motorcycles are unignorable near-ground pollutant emission sources that increase the human exposure in the dense area. However, the information of the polycyclic aromatic hydrocarbons (PAHs) emissions unde...
-
Article
Open AccessSuperhydrophobic surfaces with dual-scale roughness and water vapor-barrier property for sustainable liquid packaging applications
There is an ongoing unmet global need to manufacture novel sustainable liquid packaging materials, that are not based on plastic film or aluminum foil. Superhydrophobic coating technologies have been proposed ...
-
Article
Open AccessBioactive isopimarane and 3,4-seco isopimarane diterpenoids from Isodon amethystoides
Isodon amethystoides (Lamiaceae) is a popular plant in folk medicine in the southern provinces of China. Our phytochemical investigation of the twigs and leaves of this plant led to the discovery of five new dite...
-
Article
Predicting job finish time based on parameter features and running logs in supercomputing system
Accurate job finish time estimation is one of the key parts of scheduling strategy design in supercomputing systems. Existing research works concentrate on designing a better or more complex machine learning m...
