1,376 Result(s)
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Zhen Zhang
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Article
Open AccessA broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug
SARS-CoV-2 infection is initiated by Spike glycoprotein binding to the human angiotensin-converting enzyme 2 (ACE2) receptor via its receptor binding domain. Blocking this interaction has been proven to be an ...
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miR-338-5p regulated the NF-κB/MAPK pathway to alleviate inflammation and oxidative stress by targeting IL-6 in rats with atrial fibrillation
The aim of this study was to investigate the functional effect of miR-338-5p targeting IL-6 on NF-κB/MAPK pathway-mediated inflammation and oxidative stress in atrial fibrillation (AF) rats. AF model rats were...
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Effect of microalloying on wettability and interface characteristics of Zr-based bulk metallic glasses with W substrate
The infiltration casting method is widely employed for the preparation of ex-situ composite materials. However, the production of composite materials using this method must necessitates a comprehensive underst...
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Open AccessComparison of tacrolimus with or without prednisone therapy in primary membranous nephropathy: a retrospective clinical study
Previous studies showed tacrolimus monotherapy and dual therapy with tacrolimus and prednisone as effective treatment modalities in managing membranous nephropathy. However, few studies have compared these the...
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Open AccessNanotransistor-based gas sensing with record-high sensitivity enabled by electron trap** effect in nanoparticles
Highly sensitive, low-power, and chip-scale H2 gas sensors are of great interest to both academia and industry. Field-effect transistors (FETs) functionalized with Pd nanoparticles (PdNPs) have recently emerged a...
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The role of soil microorganisms and physicochemical properties in determining the germinate of invasive Solidago canadensis L.
Several studies have shown that soil microorganisms and physicochemical properties are crucial for the successful colonisation of invasive plants. However, most researchers have focused merely on the impacts o...
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Species composition and distribution of common Crassostrea and Saccostrea oysters along the coast of Hainan Island
Oyster cultivation is a pivotal economic industry in Hainan Island, South China, where a high oyster species diversity is shown. However, the specific distribution and biodiversity of oyster resources in the i...
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Unwarranted Overtime: Exploring the Origins and Mitigation Strategies for Excessive Work Hours Among Employees
Modern society’s rapid change has transformed the workplace, making staff management difficult. This study examines how institutional environmental elements and workplace experiences affect employee work behav...
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Experimental and finite element analyses of seismic behavior of pile-reinforced soft clayey slope
In this study, a series of shaking table model tests and three-dimensional (3D) finite element (FE) analyses were performed to mainly investigate the seismic deformations of clayey slopes reinforced by differe...
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Open AccessClathrin mediates membrane fission and budding by constricting membrane pores
Membrane budding, which underlies fundamental processes like endocytosis, intracellular trafficking, and viral infection, is thought to involve membrane coat-forming proteins, including the most observed clath...
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Open AccessIdentification of a new HIV-1 circulating recombinant form (CRF159_01103) derived from CRF103_01B and CRF01_AE in Hebei Province, China
Recombinant HIV-1 genomes identified in three or more epidemiological unrelated individuals are defined as circulating recombinant forms (CRFs). CRFs can further recombine with other pure subtypes or recombina...
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Power Grid Resource Data Homologous Maintenance Based on Complex Representation Disambiguation Model Component
Power grid resource planning is the key link of stable power supply and the important engine of smart grid system construction. The same source maintenance of power grid resources is a heavy systematic work, i...
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Open AccessZNPs reduce epidermal mechanical strain resistance by promoting desmosomal cadherin endocytosis via mTORC1-TFEB-BLOC1S3 axis
Zinc oxide nanoparticles (ZNPs) are widely used in sunscreens and nanomedicines, and it was recently confirmed that ZNPs can penetrate stratum corneum into deep epidermis. Therefore, it is necessary to determi...
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Medical Image Data Security Risk Identification Based on 6G Wireless Sensor Networks and AI-Assisted Technology
This study presents a novel technique to protect medical image data from security risks under 6G wireless technology-based communications called FUZET—Fuzzy Encryption for medical image data. This innovative a...
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Open AccessHotspots and trends in health-oriented physical literacy research: a visual analysis based on the WOS database
The World Health Organization has proposed that physical activity is a meaningful way to improve the quality of human life and reduce the probability of chronic non-communicable diseases and that humans should...
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High-Temperature Creep Behavior of Mg-9Gd-2Nd-1Ca-0.5Zr Alloy
The creep behaviors of Mg-9Gd-2Nd-1Ca-0.5Zr alloy under the temperature 200-250 °C and the applied stress 50-90 MPa for 100 h were studied in a typical creep testing machine. The stress exponent n at different st...
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Drosophila Tak1 Mediates the Condensation and Deubiquitinase Activity of Otu in a Kinase-Independent Manner
In the intricate molecular world, post-translational modifications play pivotal roles in modulating protein activity and function. The Drosophila melanogaster genome encodes an array of enzymes to mediate these p...
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Correction to: Safety and immunogenicity of SARS-CoV-2 vaccines in Chinese patients with cirrhosis: a prospective multicenter study
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Electroless plating catalyzed by 3D Cu NWs arrays on insulating substrate with enhanced adhesion
The catalytic electroless plating on insulating substrate holds great potential in additive manufacturing of printing circuits. A tri-layer interpenetration architecture was constructed to improve the peeling ...
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Transforming low-quality cotton fibers into dye adsorbents
Low-quality cotton fibers are a low-value waste material within the cotton industry. Upcycling and transforming into high-value materials are highly desired. This study investigates upcycling fibers into hydro...
