830 Result(s)
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Article
Open AccessPurification and characterization of recombinant murine endostatin in E. coli
Endostatin, a carboxyl-terminal fragment of collagen XVIII is known as an anti-angiogenic agent, that specifically inhibits the proliferation of endothelial cell and the growth of several primary tumor. We rep...
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Open AccessCharacterization of yeast deoxyhypusine synthase: PKC-dependent phosphorylation in vitro and functional domain identification
The biosynthesis of hypusine [Nε-(4-amino-2-hydroxybutyl)-lysine] occurs in the eIF-5A precursor protein through two step posttranslational modification involving deoxyhypusine synthase which catalyzes transfe...
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Open AccessThe inhibitory effects of recombinant plasminogen kringle 1-3 on the neovascularization of rabbit cornea induced by angiogenin, bFGF, and VEGF
Angiostatin is a potent angiogenesis inhibitor that is composed of the first four kringles of plasminogen fragment. Angiostatin with one less kringle molecule (kringle 1 to 3) was recently demonstrated to be a...
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Spatial distribution of allozyme polymorphisms following clonal and sexual reproduction in populations of Rhus javanica (Anacardiaceae)
Rhus javanica L. (Anacardiaceae), a dioecious tree with both sexual reproduction and clonal growth, is widely distributed in warm temperate, subtropical, and tropical regions in east Asia. We used allozyme loci a...
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Clonal and spatial genetic structure in Eurya emarginata (Theaceae)
Eurya emarginata (Thunb.) Makino (Theaceae) is a dioecious, insect-pollinated tree, which combines sexual reproduction and clonal spread. It is narrowly distributed in coastal areas from southern China, along sou...
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Article
Spontaneous spinal subdural hematoma with spontaneous resolution
Study design: Single patient case report.
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Open AccessThe mucosal adjuvanticity of two nontoxic mutants of Escherichia coli heat-labile enterotoxin varies with immunization routes
Escherichia coli heat-labile enterotoxin (LT), which causes a characteristic diarrhea in humans and animals, is a strong mucosal immunogen and has powerful mucosal adjuvant activity towards coadministered unre...
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Open AccessIdentification of Escherichia coli 8-oxoguanine endonuclease
7,8-Dihydro-8-oxoguanine (oh8Gua) endonuclease is a DNA repair enzyme in Escherichia coli to remove oh8Gua, a promutagenic DNA adduct. Due to the unique mode of enzyme action and substrate specificity, this DN...
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Article
Spatial genetic structure in a Neolitsea sericea population (Lauraceae)
Neolitsea sericea (Bl.) Koidz. (Lauraceae) is a dioecious, insect-pollinated, and broad-leaved evergreen tree with bird-dispersed seeds. We used allozyme loci, F-statistics, and spatial autocorrelation statistics...
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Neutralizing antibody provided protection against enterovirus type 71 lethal challenge in neonatal mice
Experimental infection with enterovirus type 71 (EV71) induced death in neonatal mice in an age- and dose-dependent manner. The mortality rate was 100% following intraperitoneal inoculation 1-day-old ICR mice ...
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Open AccessAssociation of castration-dependent early induction of c-myc expression with a cell proliferation of the ventral prostate gland in rat
The protooncogene c-myc is known to be associated with both cell proliferation and apoptosis. The possible cellular affects of castration on the ventral prostate gland of rat as well as the relationship to a c...
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Open AccessAssociation between cyclo-oxygenase-2 overexpression and missense p53 mutations in gastric cancer
Wild-type p53 competitively binds to the promoter region of COX-2 in vitro and inhibits its transcription. We examined the association between p53 mutation and COX-2 expression in gastric cancer. COX-2 over-expre...
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Allelic imbalance in lung cancers of nonsmokers in Hong Kong
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Article
Surgical treatment for thoracic spinal stenosis
Objectives: To describe the underlying causes, surgical results and prognostic factors in thoracic stenosis causing myelopathy.
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Article
Open AccessCloning of BNIP3h, a member of proapoptotic BNIP3 family genes
Apoptosis is regulated by interaction of antiapoptotic Bcl-2 family proteins with various proapoptotic proteins, several of which are also members of the Bcl-2 family. BNIP3 (formerly NIP3) is a proapoptotic m...
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Open AccessThe stimulatory effect of IL-1β on the insulin secretion of rat pancreatic islet is not related with iNOS pathway
Interleukin 1 (IL-1) is a pleiotropic cytokine with the potential to destroy pancreatic β-cells, and thought to be involved in the pathogenesis of type I diabetes mellitus. Expression of inducible nitric oxide...
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Open AccessEnhanced expression of neuronal nitric oxide synthase and phospholipase C-γ1 in regenerating murine neuronal cells by pulsed electromagnetic field
Pulsed electromagnetic field (PEMF) has been shown to improve the rate of peripheral nerve regeneration. In the present study we investigated the expression of neuronal nitric oxide synthase (nNOS) and phospho...
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MRI confirmed cervical cord injury caused by spinal manipulation in a Chinese patient
Objective: To report a rare case of cervical cord injury caused by spinal manipulation in a Chinese patient.
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Open AccessEffects of estrogen receptor and estrogen on the chromatin structure in estrogen receptor stable transfectants
The estrogen receptor (ER), a member of the nuclear hormone receptor superfamily recruits coactivators that modify local chromatin structure. Here we investigated the effect of the estrogen receptor and estrog...
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Open AccessRole of Ca(2+) in diallyl disulfide-induced apoptotic cell death of HCT-15 cells
Diallyl disulfide (DADS) induced apoptosis through the caspase-3 dependent pathway in leukemia cells was earlier reported from this laboratory. In this study, we investigated the involvement of Ca(2+) in DADS-...
