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    Article

    Ginsenoside-Rb1 acts as a weak phytoestrogen in MCF-7 human breast cancer cells

    Ginseng has been recommended to alleviate the menopausal symptoms, which indicates that components of ginseng very likely contain estrogenic activity. We have examined the possibility that a component ofPanax gin...

    Young Joo Lee, Young Ran **, Won Chung Lim, Wan Kyu Park in Archives of Pharmacal Research (2003)

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    Article

    Ginsenoside Rc and Re stimulate c-Fos expression in MCF-7 human breast carcinoma cells

    We have found that ginsenoside Rc and Re induce c-fos in MCF-7 human breast carcinoma cells at both the mRNA and protein levels. However, neither ginsenoside activated the expression of reporter gene under the...

    Young Joo Lee, Young Ran **, Won Chung Lim, Sang Mi Ji in Archives of Pharmacal Research (2003)

  3. Article

    Open Access

    Effects of estrogen receptor and estrogen on the chromatin structure in estrogen receptor stable transfectants

    The estrogen receptor (ER), a member of the nuclear hormone receptor superfamily recruits coactivators that modify local chromatin structure. Here we investigated the effect of the estrogen receptor and estrog...

    Young Joo Lee, Won Chung Lim, Ying Hua ** in Experimental & Molecular Medicine (2002)