-
Article
Reduced toxicity (FluBu3) versus myeloablative (BuCy) conditioning in acute myeloid leukemia patients who received first allogeneic hematopoietic stem cell transplantation in measurable residual disease-negative CR1
In the present study, reduced toxicity (FluBu3) and myeloablative (BuCy) conditioning were compared in patients with AML who received first allogeneic HSCT in MRD-negative CR1. The study included 124 adult pat...
-
Article
Real-world treatment outcomes of carfilzomib plus dexamethasone in patients with relapsed and/or refractory multiple myeloma, focusing on the impact of trial-fitness: CAtholic REsearch network for Multiple Myeloma study (CAREMM-2203)
Carfilzomib plus dexamethasone (Kd) is widely used in patients with relapsed and/or refractory multiple myeloma (RRMM). However, the treatment outcomes of Kd, especially in trial-unfit patients, have not been ...
-
Article
Marrow stimulation procedures for high-grade cartilage lesions during surgical repair of medial meniscus root tear yielded suboptimal outcomes, whilst small lesions showed surgical eligibility
To investigate the surgical outcomes of arthroscopic pull-out repair for medial meniscus root tear (MMRT) combined with the marrow stimulation procedures (MSP) for accompanying high-grade cartilage lesions.
-
Article
Comparisons of efficacy between frontline treatment with bortezomib-melphalan-prednisone and lenalidomide-dexamethasone for transplant-ineligible multiple myeloma: a multicenter real-world based registry report, CAREMM-2102 study
Bortezomib-melphalan-prednisone (VMP) and lenalidomide-dexamethasone (Rd) remain the standard treatments for transplant-ineligible patients with newly diagnosed multiple myeloma (NDMM). This study aimed to com...
-
Article
Microscopic Analysis of Magnetite Dissolution into Cu2S–FeS Matte with Gas Generation Using In Situ Observation
Solid magnetite inhibits suspended matte in slag from being absorbed into the matte phase during copper smelting using flash furnaces, leading to copper losses. Therefore, rapid magnetite removal by reaction w...
-
Article
Open AccessML-based sequential analysis to assist selection between VMP and RD for newly diagnosed multiple myeloma
Optimal first-line treatment that enables deeper and longer remission is crucially important for newly diagnosed multiple myeloma (NDMM). In this study, we developed the machine learning (ML) models predicting...
-
Article
High failure rate after conservative treatment for recurrent shoulder dislocation without subjective apprehension on physical examination
The purpose of this study was to investigate the outcomes of conservative treatment for recurrent shoulder dislocation without subjective apprehension, despite the presence of a Bankart lesion or glenoid defect.
-
Chapter
Singing Through Impossible Modernization: Sopyonje and National Cinema in the Era of Globalization
Sopyonje (Im Kwon-taek, 1993, South Korea) marks a turning point in the history of South Korea’s struggles with deeply ruptured and highly compressed modernity. It presents a powerful figuration of the profound d...
-
Article
Elucidation of Gas Formation Effect on Strong Inhibition of Magnetite Dissolution in Cu2S Through In-Situ Analysis of Reactive Interface
During copper smelting using a flash furnace, the solid magnetite (Fe3O4) phase that stagnates at the slag/matte interface inhibits the absorption of the suspended matte in the slag into the matte, resulting in c...
-
Article
Prognostic values of D816V KIT mutation and peri-transplant CBFB-MYH11 MRD monitoring on acute myeloid leukemia with CBFB-MYH11
Given the controversies in the prognostic value of KIT mutations and optimal thresholds and time points of MRD monitoring for AML with CBFB-MYH11, we retrospectively evaluated 88 patients who underwent allogeneic...
-
Article
Production of High-Purity TiO2 Powder from FeTiO3 via High-Temperature Sulfurization
The cost of Ti production can be reduced by replacing rutile ore with abundant and cheap ilmenite ore (FeTiO3). However, the conventional processes for Ti production, including the Kroll process, require signific...
-
Article
Comparison of HLA-matched sibling and unrelated donor transplantation in adult patients with acquired severe aplastic anemia
The recent improvements in the outcomes of severe aplastic anemia (SAA) patients who received allogeneic stem cell transplantation (SCT) from unrelated donors (URD) suggest the possibility of its alternative f...
-
Article
Development of Kinetic Model for Reactions Between Cu-Containing Multicomponent Slag and Liquid Sulfide Using Coupled Reaction Model
Copper smelting slag contains less than 2 mass pct of Cu oxide and 30–50 mass pct of FexO. Each year, the grade of copper ore decreases, while the amount of slag generated in the copper smelting process increases...
-
Article
Successful outcomes of second hematopoietic stem cell transplantation with total nodal irradiation and ATG conditioning for graft failure in adult patients with severe aplastic anemia
Data regarding the optimal approach for second allogeneic hematopoietic stem cell transplantation (HSCT) after graft failure (GF) in acquired severe aplastic anemia (SAA) are still limited and heterogeneous. W...
-
Article
Open AccessGenetic–pathologic characterization of myeloproliferative neoplasms
Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by the proliferation of one or more myeloid lineages. The current study demonstrates that three driver mutations w...
-
Article
Open AccessModel-based adaptive phase I trial design of post-transplant decitabine maintenance in myelodysplastic syndrome
This report focuses on the adaptive phase I trial design aimed to find the clinically applicable dose for decitabine maintenance treatment after allogeneic hematopoietic stem cell transplantation in patients w...
-
Article
Impact of extramedullary plasmacytomas on outcomes according to treatment approach in newly diagnosed symptomatic multiple myeloma
The prognostic impact of extramedullary plasmacytomas (EMPs) on newly diagnosed symptomatic multiple myeloma (MM) was evaluated in the context of treatment approach including autologous stem cell transplantati...
-
Article
Impact of failed response to novel agent induction in autologous stem cell transplantation for multiple myeloma
The aim of this study was to evaluate the impact of the response to induction therapy on the long-term prognosis of multiple myeloma (MM) after autologous stem cell transplantation (ASCT) in the era of novel a...
-
Article
Normal karyotype mosaicism in adult AML patients with adverse-risk and undefined karyotype: preliminary report of treatment outcomes after hematopoietic stem cell transplantation
Karyotype analysis in acute myeloid leukemia (AML) is one of the powerful prognostic factors for complete remission (CR), relapse, and overall survival (OS). Cytogenetic mosaicism is considered to be one of th...
-
Article
The efficacy of rabbit antithymocyte globulin with cyclosporine in comparison to horse antithymocyte globulin as a first-line treatment in adult patients with severe aplastic anemia: a single-center retrospective study
Antithymocyte globulin (ATG) is the drug of choice for immunosuppressive therapy (IST) in patients with severe aplastic anemia (SAA) ineligible for allogeneic stem cell transplantation. Recently, rabbit ATG wi...
