47 Result(s)
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English
Life Sciences
Biochemistry, general
Cell Biology
Li **n Cheng
Article
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Article
Seed, cutting and air-layering reproductive inefficiency of noxious woody vine Merremia biosiana and its implications for management strategy
Merremia boisiana (Gagnep) van Ooststr. is a noxious fast growing woody vine and is able to grow overtop other plants, causing the death of plants underneath and forming monospecies stand...
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Effect of Low-Intensity Pulsed Ultrasound on MMP-13 and MAPKs Signaling Pathway in Rabbit Knee Osteoarthritis
We evaluated the effect of low-intensity pulsed ultrasound (LIPUS) on MMP-13 and MAPKs expression in rabbit knee osteoarthritis (OA). For this purpose, 18 New Zealand white rabbits were randomly and equally di...
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A novel translocation event leads to a recombinant stable chromosome with interrupted centromeric domains in rice
Rice (Oryza sativa L.) centromeres are composed of 155-bp satellite repeats (CentO), centromere-specific retrotransposon (CRR), and a variety of other repeats. Previous studies have shown that CentO and CRR eleme...
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MRE11 is required for homologous synapsis and DSB processing in rice meiosis
Mre11, a conserved protein found in organisms ranging from yeast to multicellular organisms, is required for normal meiotic recombination. Mre11 interacts with Rad50 and Nbs1/Xrs2 to form a complex (MRN/X) tha...
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Overexpression of the Mesenchymal Stem Cell Cxcr4 Gene in Irradiated Mice Increases the Homing Capacity of These Cells
The efficiency of the intravascular delivery of mesenchymal stem cells (MSCs) homing to bone marrow has been largely limited. This study aimed to evaluate the homing efficacy in irradiated mice of MSCs that ha...
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An R2R3-MYB transcription factor as a negative regulator of the flavonoid biosynthesis pathway in Ginkgo biloba
Flavonoids are secondary metabolites that contribute substantially to the quality of Ginkgo biloba. Plant flavonoid accumulation is controlled by transcriptional regulation of the genes that encode the biosynthet...
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ABI-like transcription factor gene TaABL1 from wheat improves multiple abiotic stress tolerances in transgenic plants
The phytohormone abscisic acid (ABA) plays crucial roles in adaptive responses of plants to abiotic stresses. ABA-responsive element binding proteins (AREBs) are basic leucine zipper transcription factors that...
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Noscapine Increases the Sensitivity of Drug-Resistant Ovarian Cancer Cell Line SKOV3/DDP to Cisplatin by Regulating Cell Cycle and Activating Apoptotic Pathways
Cisplatin is a first-line chemotherapy drug against ovarian cancer. However, its strong toxic side effects and the development of cisplatin resistance in human cancer cells seriously influence the effects of c...
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Open AccessGenes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor β
Nuclear receptor family member, Estrogen related receptor β, and the Hedgehog signal transduction pathway are both reported to relate to tumorigenesis and induced pluripotent stem cell reprogramming. We hypoth...
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Open AccessMessenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells
Orphan nuclear receptor estrogen related receptor β (Esrrb or ERRβ) is well known in stem cells and early embryonic development. However, little is known about its function in cancer.
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Open AccessCoupled electrophysiological recording and single cell transcriptome analyses revealed molecular mechanisms underlying neuronal maturation
The mammalian brain is heterogeneous, containing billions of neurons and trillions of synapses forming various neural circuitries, through which sense, movement, thought, and emotion arise. The cellular hetero...
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Open AccessAbsence of physiological Ca2+ transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation
Motor neurons control muscle contraction by initiating action potentials in muscle. Denervation of muscle from motor neurons leads to muscle atrophy, which is linked to mitochondrial dysfunction. It is known t...
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The oligosaccharyl transferase subunit STT3 mediates fungal development and is required for virulence in Verticillium dahliae
Verticillium dahliae is the most overwhelming plant pathogen, causing Verticillium wilt in a number of economic crops. The molecular mechanism is still unclear and identification of the genes inv...
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Open AccessBaicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system
In this study, the effects of Baicalin on the hyperglycemia-induced cardiovascular malformation during embryo development were investigated. Using early chick embryos, an optimal concentration of Baicalin (6 μ...
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Open AccessVascularization converts the lineage fate of bone mesenchymal stem cells to endothelial cells in tissue-engineered bone grafts by modulating FGF2-RhoA/ROCK signaling
The prevascularization of tissue-engineered bone grafts (TEBGs) has been shown to accelerate capillary vessel ingrowth in bone defect remodeling and to enhance new bone formation. However, the exact mechanisms...
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Open AccessLINC81507 act as a competing endogenous RNA of miR-199b-5p to facilitate NSCLC proliferation and metastasis via regulating the CAV1/STAT3 pathway
Lung cancer is the leading cause of cancer-related mortality worldwide. Recently, accumulating data indicate that long noncoding RNAs (LncRNAs) function as novel crucial regulators of diverse biological proces...
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Open AccessComparison of miRNA-101a-3p and miRNA-144a-3p regulation with the key genes of alpaca melanocyte pigmentation
Many miRNA functions have been revealed to date. Single miRNAs can participate in life processes by regulating more than one target gene, and more than one miRNA can also simultaneously act on one target mRNA....
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mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis
Loss of either TSC1 or TSC2 causes tuberous sclerosis complex (TSC) via activation of mTOR signaling pathway. The two prominent features of TSC are skin lesions including hypomelanic macules and benign tumors ...
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Open AccessInhibition of gap junction composed of Cx43 prevents against acute kidney injury following liver transplantation
Postoperative acute kidney injury (AKI) is a severe complication after liver transplantation (LT). Its deterioration and magnification lead to the increase in mortality. Connexin43 (Cx43) mediates direct trans...
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Open AccessProhibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure
Fatty acids are the most major substrate source for adult cardiac energy generation. Prohibitin 2 (PHB2), a highly conserved protein located in mitochondrial inner membrane, plays key roles in cellular energy ...
