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Article

Absence of physiological Ca²⁺ transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation

Motor neurons control muscle contraction by initiating action potentials in muscle. Denervation of muscle from motor neurons leads to muscle atrophy, which is linked to mitochondrial dysfunction. It is known t...

Chehade Karam, Jianxun Yi, Yajuan **ao, Kamal Dhakal, Lin Zhang… in Skeletal Muscle (2017)