-
Article
Open AccessConstruction of a predictive model and prognosis of left ventricular systolic dysfunction in patients with sepsis based on the diagnosis using left ventricular global longitudinal strain
Cardiac dysfunction, a common complication of sepsis, is associated with increased mortality. However, its risk factors are poorly understood, and a predictive model might help in the management of cardiac dys...
-
Article
NF-κB-mediated miR-650 plays oncogenic roles and activates AKT/ERK/NF-κB pathways by targeting RERG in glioma cells
Glioma is the most common cancer in the central nervous system and has a high mortality rate. Despite advances that have been made in the treatment of glioma, its prognosis still remains poor. Dysregulation of...
-
Article
Open AccessAuthor Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model
The original version of this Article omitted the following from the end of the Acknowledgements: ‘X.C. also received funding from the Shenzhen Basic Research Program JCYJ20170818140904167.’ This has now been c...
-
Article
Application of Fe-MOFs in advanced oxidation processes
Metal organic frameworks (MOFs) are novel porous materials formed by the link-up of transition metal ions through organic bridges. Fe-based metal organic frameworks (Fe-MOFs), an important branch of MOFs, not ...
-
Article
Open AccessSoluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model
Triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial surface receptor genetically linked to the risk for Alzheimer’s disease (AD). A proteolytic product, soluble TREM2 (sTREM2), is abundant...
-
Article
Open AccessAmyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)
TREM2 is an innate immune receptor specifically expressed in microglia. Coding variations in TREM2 have been reported to increase the risk for Alzheimer’s disease (AD) and other neurodegenerative diseases. Whi...
-
Article
Open AccessLRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways
Neuroinflammation is characterized by microglial activation and the increased levels of cytokines and chemokines in the central nervous system (CNS). Recent evidence has implicated both beneficial and toxic ro...
-
Article
High expression of miR-16 and miR-451 predicating better prognosis in patients with gastric cancer
To investigate the expression pattern of miR-16 and miR-451 and evaluate their prognostic value in 180 GC patients undergoing surgery.
-
Article
Expression and prognostic value of miR-92a in patients with gastric cancer
MicroRNA (miR)-92 expression is often aberrant in human cancers. However, its expression in gastric carcinoma and its relation to clinicopathological features and prognosis are unclear.
-
Article
Open AccessLocal application of rapamycin reduces epidural fibrosis after laminectomy via inhibiting fibroblast proliferation and prompting apoptosis
Epidural fibrosis is a common complication after laminectomy. It is associated with intractable lower back pain and additional complications. To date, no study has evaluated whether the local application of ra...
-
Article
Open AccessReduction of intraarticular adhesion of knee by local application of rapamycin in rabbits via inhibition of fibroblast proliferation and collagen synthesis
The formation of intraarticular adhesion is a common complication after total knee arthroplasty or anterior cruciate ligament reconstruction. Previously, little research was reported regarding whether the loca...
-
Article
Open AccessReduction of intraarticular adhesion by topical application of colchicine following knee surgery in rabbits
The aim of this study was to investigate the efficacy of topical application of colchicine in reducing intraarticular adhesion in rabbits. Thirty-six rabbits were randomly and equally divided into three groups...
-
Article
Association between CTLA-4 genetic polymorphisms and susceptibility to osteosarcoma in Chinese Han population
Osteosarcoma (OS) is the most common malignant primary bone tumor in the world. The cytotoxic T-lymphocyte antigen-4 gene (CTLA-4) is an important candidate gene for influencing the development of OS. This study ...
-
Article
Simultaneous Determination of High-Density Lipoprotein, Very Low-Density Lipoprotein and Low-Density Lipoprotein Subclass in Human Serum by Microchip CE
Lipoproteins, especially high-density lipoproteins (HDL), very low-density lipoproteins (VLDL) and small, dense low-density lipoprotein (sdLDL), are believed to play an important role in the development of ath...
-
Article
Effect of Low-Intensity Pulsed Ultrasound on MMP-13 and MAPKs Signaling Pathway in Rabbit Knee Osteoarthritis
We evaluated the effect of low-intensity pulsed ultrasound (LIPUS) on MMP-13 and MAPKs expression in rabbit knee osteoarthritis (OA). For this purpose, 18 New Zealand white rabbits were randomly and equally di...
-
Article
Open AccessThe effect of combination therapy of allicin and fenofibrate on high fat diet-induced vascular endothelium dysfunction and liver damage in rats
It is designed to investigate the effects of combination therapy of allicin and fenofibrate on the endothelial and liver functions in rats with hyperlipidemia.
-
Article
Modeling of the separation performance of nanofiltration membranes and its role in the applications of nanofiltration technology in product separation processes
Although there is a voluminous literature on the determination of structural parameters (the pore radius, the ratio of membrane porosity to membrane thickness) of a nanofiltration (NF) membrane and its separat...
