-
Article
Open AccessResearch progress on the role of extracellular vesicles in neurodegenerative diseases
Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and Huntington’s disease, affect millions of people worldwide. Tremendous efforts have been put into...
-
Article
Open AccessHCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy
Renal inflammation and fibrosis are the common pathways leading to progressive chronic kidney disease (CKD). We previously identified hematopoietic cell kinase (HCK) as upregulated in human chronic allograft i...
-
Article
Open AccessComparison of the Variability of Small Extracellular Vesicles Derived from Human Liver Cancer Tissues and Cultured from the Tissue Explants Based on a Simple Enrichment Method
A potential use of small extracellular vesicles (sEVs) for diagnostic and therapeutic purposes has recently generated a great interest. sEVs, when purified directly from various tissues with proper procedures,...
-
Article
Open AccessRtn1a-Mediated Endoplasmic Reticulum Stress in Podocyte Injury and Diabetic Nephropathy
We previously reported a critical role of reticulon (RTN) 1A in mediating endoplasmic reticulum (ER) stress in kidney tubular cells and the expression of RTN1A correlates with the renal function and the severi...
-
Article
Open AccessErratum: RTN1 mediates progression of kidney disease by inducing ER stress
Nature Communications 6: Article number: 7841 (2015); Published: 31 July 2015; Updated: 22 October 2015. The original version of the Supplementary Information attached to this Article did not contain Supplemen...
-
Article
Open AccessRTN1 mediates progression of kidney disease by inducing ER stress
Identification of new biomarkers and drug targets for chronic kidney disease (CKD) is required for the development of more effective therapy. Here we report an association between expression of reticulon 1 (RT...
-
Article
Effect of nitrite exposure on metabolic response in the freshwater prawn Macrobrachium nipponense
The metabolic response of the freshwater prawn, Macrobrachium nipponense to nitrite toxicity was evaluated. The prawns were exposed to 0, 1, 2, 3 and 4 mg L−1 NO2-N concentrations for 48 h. The metabolic paramete...
