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Publisher Correction: A systems approach identifies HIPK2 as a key regulator of kidney fibrosis
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Open AccessErratum: RTN1 mediates progression of kidney disease by inducing ER stress
Nature Communications 6: Article number: 7841 (2015); Published: 31 July 2015; Updated: 22 October 2015. The original version of the Supplementary Information attached to this Article did not contain Supplemen...
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Open AccessRTN1 mediates progression of kidney disease by inducing ER stress
Identification of new biomarkers and drug targets for chronic kidney disease (CKD) is required for the development of more effective therapy. Here we report an association between expression of reticulon 1 (RT...
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Article
The primary glomerulonephritides: a systems biology approach
The integration of omics analyses of primary glomerular diseases with data from clinical and histopathological studies is expected to advance our understanding of the molecular basis of these diseases and lead...
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Molecular targets for treatment of kidney fibrosis
Renal fibrosis is the culmination of processes driven by signaling pathways involving transforming growth factor-β family of cytokines, connective-tissue growth factor, nuclear factor κB, Wnt/β-catenin, Notch,...
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Article
A systems approach identifies HIPK2 as a key regulator of kidney fibrosis
HIV infection is often associated with severe nephropathy, including renal fibrosis. John He and his colleagues have used a systems biology approach in a mouse model of HIV infection to identify the key factor...
