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Article
Predictive analysis of breast cancer response to neoadjuvant chemotherapy through plasma metabolomics
Preoperative chemotherapy is a critical component of breast cancer management, yet its effectiveness is not uniform. Moreover, the adverse effects associated with chemotherapy necessitate the identification of...
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Article
Open AccessAcute arterial occlusive disease due to tumor thrombus from lung metastasis of breast cancer with cartilaginous and osseous metaplasia: a case report
Tumor embolization due to venous infiltration of breast cancer pulmonary metastases is very rare.
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Article
Open AccessIntra-body dynamics of d-serine reflects the origin of kidney diseases
d-Serine, present only in trace amounts in humans, is now recognized as a biomarker of chronic kidney disease (CKD). CKD is heterogeneous in its original kidney diseases, whose diagnoses require kidney biopsy. .....
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Article
Open AccessHigh expression of soluble CD155 in estrogen receptor-negative breast cancer
The poliovirus receptor (CD155) is expressed ubiquitously at low levels on both hematopoietic and nonhematopoietic cells, but its expression is upregulated in various tumor cells. An activating receptor DNAM-1...
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Article
Preoperative diagnosis of a giant cell tumor of soft tissue arising from the breast by ultrasound-guided core needle biopsy
Giant cell tumors of soft tissue (GCT-ST) arising in the breast are extremely rare. Herein, we report a case of a 45-year-old woman with a 5-cm mass in her left breast. Ultrasonography revealed a mainly well-c...
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Article
Open AccessD-Serine reflects kidney function and diseases
D-Amino acids, long-term undetected enantiomers of L-amino acids, are now emerging as potential biomarkers, especially for kidney diseases. Management of chronic kidney disease (CKD), a global problem with its hi...
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Article
Open AccessAntibodies to a CA 19-9 Related Antigen Complex Identify SOX9 Expressing Progenitor Cells In Human Foetal Pancreas and Pancreatic Adenocarcinoma
The Sialyl Lewis A antigen, or CA 19-9, is the prototype serum biomarker for adenocarcinoma of the pancreas. Despite extensive clinical study of CA 19-9 in gastrointestinal malignancies, surprisingly little is...
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Article
Chemically defined and growth-factor-free culture system for the expansion and derivation of human pluripotent stem cells
The large-scale and cost-effective production of quality-controlled human pluripotent stem cells (hPSCs) for use in cell therapy and drug discovery would ideally require a chemically defined xenobiotic-free cu...
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Article
A case of hemorrhagic cystitis caused by nab-paclitaxel
Nab-paclitaxel (nab-PTX) is a nanoparticle albumin-bound paclitaxel and, as such, is free of solvents like ethanol and polyoxyethylene castor oil. The absence of solvents from this formulation has several prac...
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Article
Loss of SDHB Elevates Catecholamine Synthesis and Secretion Depending on ROS Production and HIF Stabilization
Germline mutations in genes encoding succinate dehydrogenase subunits are associated with the development of familial pheochromocytomas and paragangliomas [hereditary paraganglioma/pheochromocytoma syndrome (H...
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Article
Malignant lymphoma of the breast in a male patient: ultrasound imaging features
Non-Hodgkin lymphoma (NHL) of the breast is a rare disease. Herein, we report a rare case of secondary involvement of the breast by NHL in a male patient and the ultrasound imaging findings. A 70-year-old man ...
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Article
Extreme response to nab-paclitaxel and trastuzumab treatment in two patients with locally advanced or recurrent breast cancer
Nab-paclitaxel is a novel nanoparticle, albumin-bound paclitaxel that is free of solvents. The absence of solvents allows nab-paclitaxel to be administered without the premedication used routinely for the prev...
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Chapter
Cellular-Type Hemoglobin-Based Oxygen Carrier as a Resuscitative Fluid for Hemorrhagic Shock: Acute and Long-Term Safety Evaluation Using Beagle Dogs
Hemoglobin-vesicles (HbV, d = 251 nm) are an artificial oxygen carrier encapsulating a concentrated Hb solution in polyethylene glycol-modified phospholipid vesicles (liposomes). Their safety and efficacy as arti...
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Chapter
Serum-free medium for normal human melanocytes
MM-4 melanocyte growth medium supplemented with phorbol-12-myri state 13-acetate (PMA), cholera toxin and bovine pituitary extract (BPE) supported the growth of normal human melanocytes under the serum-free co...
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Chapter
A Salicide Base Contact Technology (SCOT) for Use in High Speed Bipolar VLSI
This chapter describes a new process technology called Salicide (self- aligned silicide) base COntact Technology (SCOT), that is applied for realizing high performance prescaler IC and high-gate-density master...
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Article
Identification of estrogen-inducible growth factors (estromedins) for rat and human mammary tumor cells in culture
The role of polypeptide growth factors (estromedins) as mediators of estrogen-responsive mammary tumor growth is studied in this report. Three possible new mechanisms were investigated that include endocrine, ...
