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    Chemically defined and growth-factor-free culture system for the expansion and derivation of human pluripotent stem cells

    The large-scale and cost-effective production of quality-controlled human pluripotent stem cells (hPSCs) for use in cell therapy and drug discovery would ideally require a chemically defined xenobiotic-free cu...

    Shin-ya Yasuda, Tatsuhiko Ikeda, Hosein Shahsavarani… in Nature Biomedical Engineering (2018)

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    Wnt/β-catenin Signaling in Embryonic Stem Cell Self-renewal and Somatic Cell Reprogramming

    Embryonic stem cells and induced pluripotent stem (iPS) cells are characterized by their ability to self-renew and to generate differentiated cells of all three germ layers. This potential makes them an attrac...

    Toshio Miki, Shin-ya Yasuda, Michael Kahn in Stem Cell Reviews and Reports (2011)