-
Article
Open AccessAssessment of intracranial aneurysm neck deformation after contour deployment
The contour neurovascular system (CNS) is a novel device to treat intracranial wide-necked bifurcation aneurysms, with few studies assessing its long-term effects. Particularly its impact on aneurysm morpholog...
-
Article
Open AccessImage-based hemodynamic simulations for intracranial aneurysms: the impact of complex vasculature
Hemodynamics play an important role in the assessment of intracranial aneurysm (IA) development and rupture risk. The purpose of this study was to examine the impact of complex vasculatures onto the intra-vess...
-
Article
Open AccessUnveiling rupture risk and clinical outcomes in midline aneurysms: A matched cohort analysis investigating the impact of localization within the anterior or posterior circulation
Intracranial aneurysms (IAs) located in the anterior and posterior circulations of the Circle of Willis present differential rupture risks. This study aimed to compare the rupture risk and clinical outcomes of...
-
Article
Open AccessMultimodal exploration of the intracranial aneurysm wall
Intracranial aneurysms (IAs) are pathological changes of the intracranial vessel wall, although clinical image data can only show the vessel lumen. Histology can provide wall information but is typically restr...
-
Article
Open AccessIs Accurate Lumen Segmentation More Important than Outlet Boundary Condition in Image-Based Blood Flow Simulations for Intracranial Aneurysms?
Image-based blood flow simulations are increasingly used to investigate the hemodynamics in intracranial aneurysms (IAs). However, a strong variability in segmentation approaches as well as the absence of indi...
-
Article
Open AccessA hybrid hierarchical strategy for registration of 7T TOF-MRI to 7T PC-MRI intracranial vessel data
7T time-of-flight (TOF) MRI provides high resolution for the evaluation of cerebrovascular vessels and pathologies. In combination with 4D flow fields acquired with phase-contrast (PC) MRI, hemodynamic informa...
-
Article
Open AccessDeep learning-based semantic vessel graph extraction for intracranial aneurysm rupture risk management
Intracranial aneurysms are vascular deformations in the brain which are complicated to treat. In clinical routines, the risk assessment of intracranial aneurysm rupture is simplified and might be unreliable, e...
-
Article
Open AccessSelf-calibration of C-arm imaging system using interventional instruments during an intracranial biplane angiography
To create an accurate 3D reconstruction of the vascular trees, it is necessary to know the exact geometrical parameters of the angiographic imaging system. Many previous studies used vascular structures to est...
-
Article
Open AccessVR-based training of craniotomy for intracranial aneurysm surgery
Intracranial aneurysms can be treated micro-surgically. This procedure involves an appropriate head position of the patient and a proper craniotomy. These steps enable a proper access, facilitating the subsequ...
-
Article
Open AccessVirtual embolization for treatment support of intracranial AVMs using an interactive desktop and VR application
The treatment of intracranial arteriovenous malformations (AVM) is challenging due to their complex anatomy. For this vessel pathology, arteries are directly linked to veins without a capillary bed in between....
-
Article
Open AccessDefinition and extraction of 2D shape indices of intracranial aneurysm necks for rupture risk assessment
Intracranial aneurysms are local dilations of brain vessels. Their rupture, as well as their treatment, is associated with high risk of morbidity and mortality. In this work, we propose shape indices for aneur...
-
Article
Open AccessHemodynamic Data Assimilation in a Subject-specific Circle of Willis Geometry
The anatomy of the circle of Willis (CoW), the brain’s main arterial blood supply system, strongly differs between individuals, resulting in highly variable flow fields and intracranial vascularization pattern...
-
Article
Open AccessDistance and force visualisations for improved simulation of intracranial aneurysm clip**
The treatment of cerebral aneurysms shifted from microsurgical to endovascular therapy. But for some difficult aneurysm configurations, e.g. wide neck aneurysms, microsurgical clip** is better suited. From t...
-
Article
Open AccessVICTORIA: VIrtual neck Curve and True Ostium Reconstruction of Intracranial Aneurysms
For the status evaluation of intracranial aneurysms (IAs), morphological and hemodynamic parameters can provide valuable information. For their extraction, a separation of the aneurysm sac from its parent vess...
-
Article
Open AccessComplex wall modeling for hemodynamic simulations of intracranial aneurysms based on histologic images
For the evaluation and rupture risk assessment of intracranial aneurysms, clinical, morphological and hemodynamic parameters are analyzed. The reliability of intracranial hemodynamic simulations strongly depen...
-
Article
Open AccessMultimodal validation of focal enhancement in intracranial aneurysms as a surrogate marker for aneurysm instability
Circumferential enhancement on MR vessel wall imaging has been proposed as a biomarker of a higher risk of rupture in intracranial aneurysms. Focal enhancement is frequently encountered in unruptured aneurysms...
-
Article
Open AccessCombining visual analytics and case-based reasoning for rupture risk assessment of intracranial aneurysms
Medical case-based reasoning solves problems by applying experience gained from the outcome of previous treatments of the same kind. Particularly for complex treatment decisions, for example, incidentally foun...
-
Article
Open AccessMultiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters
Geometric parameters have been proposed for prediction of cerebral aneurysm rupture risk. Predicting the rupture risk for incidentally detected unruptured aneurysms could help clinicians in their treatment dec...
