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Article
Open AccessIs Accurate Lumen Segmentation More Important than Outlet Boundary Condition in Image-Based Blood Flow Simulations for Intracranial Aneurysms?
Image-based blood flow simulations are increasingly used to investigate the hemodynamics in intracranial aneurysms (IAs). However, a strong variability in segmentation approaches as well as the absence of indi...
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Article
Open AccessSelf-calibration of C-arm imaging system using interventional instruments during an intracranial biplane angiography
To create an accurate 3D reconstruction of the vascular trees, it is necessary to know the exact geometrical parameters of the angiographic imaging system. Many previous studies used vascular structures to est...
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Chapter and Conference Paper
Predicting Aneurysm Rupture with Deep Learning on 3D Models
Rupture risk analysis of intracranial aneurysms is important for treatment decisions. Morphological parameters like size, diameter or aspect ratio are used to capture the relevant aspects of the aneurysm shape...
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Article
Open AccessDefinition and extraction of 2D shape indices of intracranial aneurysm necks for rupture risk assessment
Intracranial aneurysms are local dilations of brain vessels. Their rupture, as well as their treatment, is associated with high risk of morbidity and mortality. In this work, we propose shape indices for aneur...
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Article
Open AccessVICTORIA: VIrtual neck Curve and True Ostium Reconstruction of Intracranial Aneurysms
For the status evaluation of intracranial aneurysms (IAs), morphological and hemodynamic parameters can provide valuable information. For their extraction, a separation of the aneurysm sac from its parent vess...
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Article
Open AccessTocilizumab-associated posterior reversible encephalopathy syndrome in giant-cell arteritis – case report
We describe one of the first cases of a Posterior reversible encephalopathy syndrome (PRES) under tocilizumab as treatment of Giant cell arteritis (GCA).
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Article
Open AccessCombining visual analytics and case-based reasoning for rupture risk assessment of intracranial aneurysms
Medical case-based reasoning solves problems by applying experience gained from the outcome of previous treatments of the same kind. Particularly for complex treatment decisions, for example, incidentally foun...
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Article
Open AccessStent-assisted coiling of broad-necked intracranial aneurysms with a new braided microstent (Accero): procedural results and long-term follow-up
Intracranial stents have expanded endovascular therapy options for intracranial aneurysms. The braided Accero stent is available for clinical use since May 2015. To date, no clinical reports on the stent are a...
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Chapter and Conference Paper
VICTORIA
For the characterization of intracranial aneurysms, morphological and hemodynamic parameters provide valuable information. To evaluate these quantities, the separation of the aneurysm from its parent vessel is...
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Article
Deployment of flow diverter devices: prediction of foreshortening and validation of the simulation in 18 clinical cases
Flow diverter (FD) devices show severe shortening during deployment in dependency of the vessel geometry. Valid information regarding the geometry of the targeted vessel is therefore mandatory for correct devi...
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Article
Flow-splitting-based computation of outlet boundary conditions for improved cerebrovascular simulation in multiple intracranial aneurysms
Image-based hemodynamic simulations have great potential for precise blood flow predictions in intracranial aneurysms. Due to model assumptions and simplifications with respect to boundary conditions, clinical...
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Article
Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—phase II: rupture risk assessment
Assessing the rupture probability of intracranial aneurysms (IAs) remains challenging. Therefore, hemodynamic simulations are increasingly applied toward supporting physicians during treatment planning. Howeve...
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Article
Open AccessMultiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters
Geometric parameters have been proposed for prediction of cerebral aneurysm rupture risk. Predicting the rupture risk for incidentally detected unruptured aneurysms could help clinicians in their treatment dec...
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Article
Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Phase I: Segmentation
Advanced morphology analysis and image-based hemodynamic simulations are increasingly used to assess the rupture risk of intracranial aneurysms (IAs). However, the accuracy of those results strongly depends on...
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Article
Semiautomatic neck curve reconstruction for intracranial aneurysm rupture risk assessment based on morphological parameters
Morphological parameters of intracranial aneurysms (IAs) are well established for rupture risk assessment. However, a manual measurement is error-prone, not reproducible and cumbersome. For an automatic extrac...
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Chapter and Conference Paper
Impact of Gradual Vascular Deformations on the Intra-aneurysmal Hemodynamics
The treatment of intracranial aneurysms based on stentassisted coiling often leads to local vascular deformations. Patient-specific data of an aneurysm in the pre interventional and follow-up state is used to ...
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Article
Multiple intracranial aneurysms: a direct hemodynamic comparison between ruptured and unruptured vessel malformations
Despite numerous studies addressing the rupture risk of intracranial aneurysms that have been published, the assessment thereof still remains challenging. Image-based simulations enable a precise prediction of...
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Chapter and Conference Paper
Automatic Viewpoint Selection for Exploration of Time-Dependent Cerebral Aneurysm Data
This paper presents an automatic selection of viewpoints, forming a camera path, to support the exploration of cerebral aneurysms. Aneurysms bear the risk of rupture with fatal consequences for the patient. Fo...
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Article
Experimental investigation of intravascular OCT for imaging of intracranial aneurysms
Rupture risk assessment of an intracranial aneurysm (IA) is an important factor for indication of therapy. Until today, there is no suitable objective prediction method. Conventional imaging modalities cannot ...
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Chapter and Conference Paper
Evaluation of Time-Dependent Wall Shear Stress Visualizations for Cerebral Aneurysms
For the rupture risk assessment of cerebral aneurysms, the blood flow is approximated using computational fluid dynamics (CFD). Unsteady CFD inflow conditions yield time-dependent vector fields, from which the...
