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Article
Open AccessUnveiling rupture risk and clinical outcomes in midline aneurysms: A matched cohort analysis investigating the impact of localization within the anterior or posterior circulation
Intracranial aneurysms (IAs) located in the anterior and posterior circulations of the Circle of Willis present differential rupture risks. This study aimed to compare the rupture risk and clinical outcomes of...
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Article
Open AccessVR-based training of craniotomy for intracranial aneurysm surgery
Intracranial aneurysms can be treated micro-surgically. This procedure involves an appropriate head position of the patient and a proper craniotomy. These steps enable a proper access, facilitating the subsequ...
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Article
Open AccessTheranostic applications of optical coherence tomography in neurosurgery?
In light of our own experiences, we value the existing literature to critically point out possible “near” future applications of optical coherence tomography (OCT) as an intraoperative neurosurgical guidance t...
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Article
Open AccessDefinition and extraction of 2D shape indices of intracranial aneurysm necks for rupture risk assessment
Intracranial aneurysms are local dilations of brain vessels. Their rupture, as well as their treatment, is associated with high risk of morbidity and mortality. In this work, we propose shape indices for aneur...
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Article
Open AccessDistance and force visualisations for improved simulation of intracranial aneurysm clip**
The treatment of cerebral aneurysms shifted from microsurgical to endovascular therapy. But for some difficult aneurysm configurations, e.g. wide neck aneurysms, microsurgical clip** is better suited. From t...
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Article
Open AccessVICTORIA: VIrtual neck Curve and True Ostium Reconstruction of Intracranial Aneurysms
For the status evaluation of intracranial aneurysms (IAs), morphological and hemodynamic parameters can provide valuable information. For their extraction, a separation of the aneurysm sac from its parent vess...
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Chapter and Conference Paper
Interactive Visualization of Cerebral Blood Flow for Arteriovenous Malformation Embolisation
Arteriovenous malformations in the brain are abnormal connections between cerebral arteries and veins without the capillary system. They might rupture with fatal consequences. Their treatment is highly patient...
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Article
Open AccessCombining visual analytics and case-based reasoning for rupture risk assessment of intracranial aneurysms
Medical case-based reasoning solves problems by applying experience gained from the outcome of previous treatments of the same kind. Particularly for complex treatment decisions, for example, incidentally foun...
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Article
CCM1/KRIT1 mutation in monozygotic twins of a polyzygotic triplet birth: genetic, clinical and radiological characteristics
Cerebral cavernous malformations are focal vascular lesions of the brain, occurring sporadically or as an autosomal dominant familial form. The genetic background influences not only the clinical course but al...
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Article
Evaluation of the risk of rupture of intracranial aneurysms in patients with aneurysmal subarachnoid hemorrhage according to the PHASES score
The PHASES score was developed to determine the risk of rupture of un-ruptured intracranial aneurysms (UIAs). The purposes of the current study were to apply this score on patients with actually ruptured intra...
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Article
Brain arteriovenous malformations: implications of CEACAM1-positive inflammatory cells and sex on hemorrhage
Brain arteriovenous malformations (bAVMs) are severe conditions which, upon rupture, cause debilitating neurological deficits and even death. The exact cellular and molecular mechanisms associated with bAVM ru...
