Cerebral Aneurysm Detection and Analysis
First Challenge, CADA 2020, Held in Conjunction with MICCAI 2020, Lima, Peru, October 8, 2020, Proceedings
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Chapter and Conference Paper
Deep Learning-Based Pulmonary Artery Surface Mesh Generation
Properties of the pulmonary artery play an essential role in the diagnosis and treatment planning of diseases such as pulmonary hypertension. Patient-specific simulation of hemodynamics can support the plannin...
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Article
Open AccessCT-based comparison of porcine, ovine, and human pulmonary arterial morphometry
To facilitate pre-clinical animal and in-silico clinical trials for implantable pulmonary artery pressure sensors, understanding the respective species pulmonary arteries (PA) anatomy is important. Thus, morph...
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Article
Comparison of rhinomanometric and computational fluid dynamic assessment of nasal resistance with respect to measurement accuracy
Computational fluid dynamics (CFD)-based calculation of intranasal airflow became an important method in rhinologic research. Current evidence shows weak to moderate correlation as well as a systematic underpr...
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Chapter and Conference Paper
Correction to: Cerebral Aneurysm Detection and Analysis
In the originally published version of the book the title was incorrect. The title has now been corrected from “Cerebral Aneurysm Detection” to “Cerebral Aneurysm Detection and Analysis” and the publication ha...
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Chapter and Conference Paper
Intracranial Aneurysm Rupture Prediction with Computational Fluid Dynamics Point Clouds
Intracranial aneurysms frequently cause subarachnoid hemorrhage—a life-threatening condition with a high mortality and morbidity rate. State-of-the-art methods of the rupture risk prediction combine demographi...
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Chapter and Conference Paper
CADA: Clinical Background and Motivation
Imaging of cerebral aneurysms using DSA, MRI or CTA plays a key role in diagnosis, decision for treatment or observation, treatment planning either as microsurgical clip** or as endovascular intervention inc...
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Chapter and Conference Paper
Cerebral Aneurysm Detection and Analysis Challenge 2020 (CADA)
Rupture of an intracranial aneurysm often results in subarachnoid hemorrhage, a life-threatening condition with high mortality and morbidity. The Cerebral Aneurysm Detection and Analysis (CADA) competition was...
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Book and Conference Proceedings
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Article
Open AccessAssessment of hemodynamic responses to exercise in aortic coarctation using MRI-ergometry in combination with computational fluid dynamics
In patients with aortic coarctation it would be desirable to assess pressure gradients as well as information about blood flow profiles at rest and during exercise. We aimed to assess the hemodynamic responses...
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Open AccessCharacterization of the Airflow within an Average Geometry of the Healthy Human Nasal Cavity
This study’s objective was the generation of a standardized geometry of the healthy nasal cavity. An average geometry of the healthy nasal cavity was generated using a statistical shape model based on 25 sympt...
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Chapter and Conference Paper
Unsupervised Learning and Statistical Shape Modeling of the Morphometry and Hemodynamics of Coarctation of the Aorta
Image-based patient-specific modeling of blood flow is a current state of the art approach in cardiovascular research proposed to support diagnosis and treatment decision. However, the approach is time-consuming,...
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Article
Open AccessSurrogates for myocardial power and power efficiency in patients with aortic valve disease
We aimed to assess surrogate markers for left ventricular (LV) myocardial power and efficiency in patients with isolated aortic stenosis (AS) and combined stenosis/regurgitation (AS/AR). In AS (n = 59), AS/AR ...
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User-dependent variability in mitral valve segmentation and its impact on CFD-computed hemodynamic parameters
While novel tools for segmentation of the mitral valve are often based on automatic image processing, they mostly require manual interaction by a proficient user. Those segmentations are essential for numerica...
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Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—phase II: rupture risk assessment
Assessing the rupture probability of intracranial aneurysms (IAs) remains challenging. Therefore, hemodynamic simulations are increasingly applied toward supporting physicians during treatment planning. Howeve...
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Article
Open AccessMultiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters
Geometric parameters have been proposed for prediction of cerebral aneurysm rupture risk. Predicting the rupture risk for incidentally detected unruptured aneurysms could help clinicians in their treatment dec...
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Article
Open AccessImpact of predictive medicine on therapeutic decision making: a randomized controlled trial in congenital heart disease
Computational modelling has made significant progress towards clinical application in recent years. In addition to providing detailed diagnostic data, these methods have the potential to simulate patient-speci...
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Article
Virtual downsizing for decision support in mitral valve repair
Various options are available for the treatment of mitral valve insufficiency, including reconstructive approaches such as annulus correction through ring implants. The correct choice of general therapy and im...
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Article
Open AccessReal-World Variability in the Prediction of Intracranial Aneurysm Wall Shear Stress: The 2015 International Aneurysm CFD Challenge
Image-based computational fluid dynamics (CFD) is widely used to predict intracranial aneurysm wall shear stress (WSS), particularly with the goal of improving rupture risk assessment. Nevertheless, concern ha...
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Article
Uncertainty Quantification for Non-invasive Assessment of Pressure Drop Across a Coarctation of the Aorta Using CFD
Numerical assessment of the pressure drop across an aortic coarctation using CFD is a promising approach to replace invasive catheter-based measurements. The aim of this study was to investigate and quantify t...
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Article
Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Phase I: Segmentation
Advanced morphology analysis and image-based hemodynamic simulations are increasingly used to assess the rupture risk of intracranial aneurysms (IAs). However, the accuracy of those results strongly depends on...
