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Article
Open AccessEndoscope-enhanced fluorescence-guided microsurgery increases survival in patients with glioblastoma
Extent of resection (EOR) predicts progression-free survival (PFS) and may impact overall survival (OS) in patients with glioblastoma. We recently demonstrated that 5-aminolevulinic acid-(5-ALA)-fluorescence-e...
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Article
Digital hands-on learning in radiology—design and evaluation of a PACS-based concept for medical students
The reorganization of the medical curriculum has increased the demands on medical didactics. For interdisciplinary fields such as radiology this offers the opportunity to be more visible in clinical medical te...
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Article
Open AccessIs Accurate Lumen Segmentation More Important than Outlet Boundary Condition in Image-Based Blood Flow Simulations for Intracranial Aneurysms?
Image-based blood flow simulations are increasingly used to investigate the hemodynamics in intracranial aneurysms (IAs). However, a strong variability in segmentation approaches as well as the absence of indi...
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Article
Open AccessThe interleukin-11 receptor variant p.W307R results in craniosynostosis in humans
Craniosynostosis is characterized by the premature fusion and ossification of one or more of the sutures of the calvaria, often resulting in abnormal features of the face and the skull. In cases in which growt...
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Article
Open AccessDeep learning-based semantic vessel graph extraction for intracranial aneurysm rupture risk management
Intracranial aneurysms are vascular deformations in the brain which are complicated to treat. In clinical routines, the risk assessment of intracranial aneurysm rupture is simplified and might be unreliable, e...
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Article
Open AccessCounteraction of inflammatory activity in CAA-related subarachnoid hemorrhage
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Chapter and Conference Paper
Geometric Deep Learning Vascular Domain Segmentation
For rupture risk assessment of intracranial aneurysms, 3D surface model extraction might be time-consuming but supports calculation of morphological and hemodynamical parameters. We present a geometric deep le...
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Article
Open AccessFlow Diverter Treatment of Ruptured Basilar Artery Perforator Aneurysms
Ruptured basilar artery perforator aneurysms (BAPAs) represent a very rare cause of subarachnoid hemorrhage and an under-reported subtype of cerebral aneurysm. There is no consensus for the optimal treatment s...
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Article
Open AccessA matter of frailty: the modified Subdural Hematoma in the Elderly (mSHE) score
The Subdural Hematoma in the Elderly (SHE) score was developed as a model to predict 30-day mortality from acute, chronic, and mixed subdural hematoma in the elderly population after minor or no trauma. Emergi...
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Article
Open AccessVirtual embolization for treatment support of intracranial AVMs using an interactive desktop and VR application
The treatment of intracranial arteriovenous malformations (AVM) is challenging due to their complex anatomy. For this vessel pathology, arteries are directly linked to veins without a capillary bed in between....
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Article
Open AccessVolumetric analysis of bilateral spinal canal decompression via hemilaminectomy versus laminoplasty in cervical spondylotic myelopathy
Cervical spondylotic myelopathy (CSM) is a degenerative process of the cervical spine requiring surgical decompression to prevent neurological deterioration. While both anterior and posterior approaches yield ...
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Article
The ReWiSed CARe Technique
Endovascular treatment of acute cerebral large vessel occlusions and concomitant atherosclerotic lesions of the ipsilateral internal carotid artery (ICA) are a matter of debate. This article reports a multi-ce...
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Article
Open AccessBridging therapy is associated with improved cognitive function after large vessel occlusion stroke – an analysis of the German Stroke Registry
The targeted use of endovascular therapy (EVT), with or without intravenous thrombolysis (IVT) in acute large cerebral vessel occlusion stroke (LVOS) has been proven to be superior compared to IVT alone. Despi...
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Article
Open AccessAngioplasty with the scepter C dual lumen balloon catheter and postprocedural result evaluation in patients with subarachnoid hemorrhage related vasospasms
Delayed cerebral ischemia is one of the leading causes of death and disability in patients with subarachnoid hemorrhage (SAH). Transluminal balloon angioplasty (TBA) is a therapeutic option for vasospasms affe...
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Article
Open AccessCorrection to: SMART coils for intracranial aneurysm repair - a single center experience
An amendment to this paper has been published and can be accessed via the original article.
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Article
Defining cutoff values for early prediction of delayed cerebral ischemia after subarachnoid hemorrhage by CT perfusion
Early prediction of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH) is essential to prevent infarction. CT perfusion (CTP) is used to identify perfusion deficits and to guide tr...
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Article
The SAVE Technique
The stent retriever assisted vacuum-locked extraction (SAVE) technique was introduced as an effective thrombectomy method in stroke patients suffering from intracranial large vessel occlusion (LVO). This artic...
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Article
Open AccessEvaluation of an optimized metal artifact reduction algorithm for flat-detector angiography compared to DSA imaging in follow-up after neurovascular procedures
Flat detector CT – angiography (FDCTA) has become a valuable imaging tool in post- and peri-interventional imaging after neurovascular procedures. Metal artifacts produced by radiopaque implants like clips or ...
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Article
Maximizing First-Pass Complete Reperfusion with SAVE
Endovascular techniques for treatment of large vessel occlusions (LVO) in patients with acute ischemic stroke (AIS) have advanced in recent years. We report a multicenter experience using a combined aspiration...
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Article
Transluminal angioplasty and stenting versus conservative treatment in patients with symptomatic basilar artery stenosis
Two recent randomized controlled trials (RCT) consistently showed superiority of aggressive medical treatment versus percutaneous transluminal angioplasty and stenting (PTAS) in patients with intracranial arte...
