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Article
Open AccessCo-localization of antibiotic resistance genes is widespread in the infant gut microbiome and associates with an immature gut microbial composition
In environmental bacteria, the selective advantage of antibiotic resistance genes (ARGs) can be increased through co-localization with genes such as other ARGs, biocide resistance genes, metal resistance genes...
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Article
Open AccessExpanding known viral diversity in the healthy infant gut
The gut microbiome is shaped through infancy and impacts the maturation of the immune system, thus protecting against chronic disease later in life. Phages, or viruses that infect bacteria, modulate bacterial ...
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Article
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants
The number and diversity of known CRISPR–Cas systems have substantially increased in recent years. Here, we provide an updated evolutionary classification of CRISPR–Cas systems and cas genes, with an emphasis on ...
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Chapter
Archaeal Viruses and Their Interactions with CRISPR-Cas Systems
Our knowledge of archaeal viruses has increased rapidly over the past four decades since the discovery of the archaeal domain. Most surprising has been the morphological diversity of crenarchaeal viruses that ...
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Article
An updated evolutionary classification of CRISPR–Cas systems
CRISPR–Cas systems provide archaea and bacteria with adaptive immunity against viruses and plasmids.
CRISPR...