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  1. Article

    Open Access

    MAGinator enables accurate profiling of de novo MAGs with strain-level phylogenies

    Metagenomic sequencing has provided great advantages in the characterisation of microbiomes, but currently available analysis tools lack the ability to combine subspecies-level taxonomic resolution and accurat...

    Trine Zachariasen, Jakob Russel, Charisse Petersen in Nature Communications (2024)

  2. Article

    Open Access

    Co-localization of antibiotic resistance genes is widespread in the infant gut microbiome and associates with an immature gut microbial composition

    In environmental bacteria, the selective advantage of antibiotic resistance genes (ARGs) can be increased through co-localization with genes such as other ARGs, biocide resistance genes, metal resistance genes...

    Xuanji Li, Asker Brejnrod, Urvish Trivedi, Jakob Russel, Jonathan Thorsen in Microbiome (2024)

  3. Article

    Open Access

    Differential responses of the gut microbiome and resistome to antibiotic exposures in infants and adults

    Despite their crucial importance for human health, there is still relatively limited knowledge on how the gut resistome changes or responds to antibiotic treatment across ages, especially in the latter case. H...

    Xuanji Li, Asker Brejnrod, Jonathan Thorsen, Trine Zachariasen in Nature Communications (2023)

  4. Article

    Open Access

    A community resource for paired genomic and metabolomic data mining

    Genomics and metabolomics are widely used to explore specialized metabolite diversity. The Paired Omics Data Platform is a community initiative to systematically document links between metabolome and (meta)gen...

    Michelle A. Schorn, Stefan Verhoeven, Lars Ridder, Florian Huber in Nature Chemical Biology (2021)

  5. Article

    Open Access

    Prenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial

    Maternal dietary interventions during pregnancy with fish oil and high dose vitamin D have been shown to reduce the incidence of asthma and wheeze in offspring, potentially through microbial effects in pregnan...

    Mathis H. Hjelmsø, Shiraz A. Shah, Jonathan Thorsen in Nature Communications (2020)

  6. Article

    Open Access

    Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

    Asthma is believed to arise through early life aberrant immune development in response to environmental exposures that may influence the airway microbiota. Here, we examine the airway microbiota during the fir...

    Jonathan Thorsen, Morten A. Rasmussen, Johannes Waage in Nature Communications (2019)

  7. Article

    Author Correction: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Evan Bolyen, Jai Ram Rideout, Matthew R. Dillon in Nature Biotechnology (2019)

  8. No Access

    Article

    Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

    Evan Bolyen, Jai Ram Rideout, Matthew R. Dillon in Nature Biotechnology (2019)

  9. Article

    Open Access

    Long-term soil metal exposure impaired temporal variation in microbial metatranscriptomes and enriched active phages

    It remains unclear whether adaptation and changes in diversity associated to a long-term perturbation are sufficient to ensure functional resilience of soil microbial communities. We used RNA-based approaches ...

    Samuel Jacquiod, Inês Nunes, Asker Brejnrod, Martin A. Hansen, Peter E. Holm in Microbiome (2018)

  10. No Access

    Article

    Soil bacteria show different tolerance ranges to an unprecedented disturbance

    Soil microbial communities have remarkable capacities to cope with ceaseless environmental changes, but little is known about their adaptation potential when facing an unprecedented disturbance. We tested the ...

    Inês Nunes, Stephanie Jurburg, Samuel Jacquiod in Biology and Fertility of Soils (2018)

  11. Article

    Open Access

    Warming, shading and a moth outbreak reduce tundra carbon sink strength dramatically by changing plant cover and soil microbial activity

    Future increases in temperature and cloud cover will alter plant growth and decomposition of the large carbon pools stored in Arctic soils. A better understanding of interactions between above- and belowground...

    Mathilde Borg Dahl, Anders Priemé, Asker Brejnrod, Peter Brusvang in Scientific Reports (2017)

  12. Article

    Open Access

    Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies

    There is an immense scientific interest in the human microbiome and its effects on human physiology, health, and disease. A common approach for examining bacterial communities is high-throughput sequencing of ...

    Jonathan Thorsen, Asker Brejnrod, Martin Mortensen, Morten A. Rasmussen in Microbiome (2016)