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Article
Open AccessCo-localization of antibiotic resistance genes is widespread in the infant gut microbiome and associates with an immature gut microbial composition
In environmental bacteria, the selective advantage of antibiotic resistance genes (ARGs) can be increased through co-localization with genes such as other ARGs, biocide resistance genes, metal resistance genes...
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Article
Open AccessDifferential responses of the gut microbiome and resistome to antibiotic exposures in infants and adults
Despite their crucial importance for human health, there is still relatively limited knowledge on how the gut resistome changes or responds to antibiotic treatment across ages, especially in the latter case. H...
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Article
Open AccessThe airway microbiota of neonates colonized with asthma-associated pathogenic bacteria
Culture techniques have associated colonization with pathogenic bacteria in the airways of neonates with later risk of childhood asthma, whereas more recent studies utilizing sequencing techniques have shown t...
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Article
Open AccessThe develo** airway and gut microbiota in early life is influenced by age of older siblings
Growing up with siblings has been linked to numerous health outcomes and is also an important determinant for the develo** microbiota. Nonetheless, research into the role of having siblings on the develo**...
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Article
Open AccessBiofilms can act as plasmid reserves in the absence of plasmid specific selection
Plasmids facilitate rapid bacterial adaptation by shuttling a wide variety of beneficial traits across microbial communities. However, under non-selective conditions, maintaining a plasmid can be costly to the...
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Article
Open AccessPersistence and progression of staphylococcal infection in the presence of public goods
Staphylococcus aureus is a prominent etiological agent of suppurative abscesses. In principle, abscess formation and purulent exudate are classical physiological features of healing and tissue repair. However, S....
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Article
Open AccessEnvironmental sha** of the bacterial and fungal community in infant bed dust and correlations with the airway microbiota
From early life, children are exposed to a multitude of environmental exposures, which may be of crucial importance for healthy development. Here, the environmental microbiota may be of particular interest as ...
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Article
Open AccessThe microbiome of captive hamadryas baboons
The hamadryas baboon (Papio hamadryas) is a highly social primate that lives in complex multilevel societies exhibiting a wide range of group behaviors akin to humans. In contrast to the widely studied human micr...
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Article
Open AccessAmplicon sequencing provides more accurate microbiome information in healthy children compared to culturing
Next-Generation Sequencing (NGS) of 16S rRNA gene is now one of the most widely used application to investigate the microbiota at any given body site in research. Since NGS is more sensitive than traditional c...
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Article
Pseudomonas aeruginosa biofilms perturb wound resolution and antibiotic tolerance in diabetic mice
Diabetic patients are more susceptible to the development of chronic wounds than non-diabetics. The impaired healing properties of these wounds, which often develop debilitating bacterial infections, significa...
