18 Result(s)

Chapter

Predicting Tofu Productivities of Soybean Varieties by Tofu Gel Centrifugation

Ten soybean varieties were selected to study their processing properties for tofu. Tofu yields varied from 70.83g to 98.70g per 30g of soybean. The yield of tofu was loosely correlated with the solid content o...

S.-J. Tsai, T. L. Hong, S. C. S. Tsou in Developments in Food Engineering (1994)

Article

A study of alpha-adrenoceptor gene polymorphisms and Alzheimer disease

There exists considerable evidence implicating abnormalities of the alpha (α)-adrenergic system in the development of Alzheimer disease (AD). We propose to investigate potential correlations between the prese...

C.-J. Hong, Y.-C. Wang, T.-Y. Liu, H.-C. Liu, S.-J. Tsai in Journal of Neural Transmission (2001)

Article

Association analysis for genetic variants of the NMDA receptor 2b subunit (GRIN2B) and Parkinson's disease

Recent studies have implicated N-methyl-D-aspartate (NMDA) receptor dysfunction in the pathogenesis and treatment of Parkinson's disease (PD). The NMDA receptor is composed of several subunits, of which, the ...

S.-J. Tsai, H.-C. Liu, T.-Y. Liu, C.-Y. Cheng, C.-J. Hong in Journal of Neural Transmission (2002)

Article

Association study of Angiotensin I-converting enzyme polymorphism and symptomatology and antidepressant response in major depressive disorders

Angiotensin-converting enzyme (ACE) inhibitor has mood-elevating effects, and central ACE activity is increased for suicidal patients. In addition, substance P (SP), which is degraded by ACE, has been implica...

C.-J. Hong, Y.-C. Wang, S.-J. Tsai in Journal of Neural Transmission (2002)

Article

Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders

The serotonin transporter (5-HTT) is the site of primary action for the selective serotonin reuptake inhibitors (SSRIs). Previous Western reports have demonstrated that the lallele of the 5-HTT gene-linked polymo...

Y W-Y Yu, S-J Tsai, T-J Chen, C-H Lin, C-J Hong in Molecular Psychiatry (2002)

Article

Association study of the dopamine and serotonin transporter genetic polymorphisms and methamphetamine abuse in Chinese males

The dopamine transporter (DAT) and the serotonin transporter (5-HTT) play important roles in methamphetamine (METH) dependence because they are the target of METH action. For this study, the association betwe...

C.-J. Hong, C.-Y. Cheng, L.-R. R. Shu, C.-Y. Yang… in Journal of Neural Transmission (2003)

Article

Association studies of the adenosine A2a receptor (1976T > C) genetic polymorphism in Parkinson’s disease and schizophrenia

Given the implications with respect to the pathogenesis of dopaminergic dysfunction in schizophrenia and Parkinson’s disease (PD), as well as the reciprocal antagonistic interactions between adenosine A2a rece...

C.-J. Hong, H.-C. Liu, T.-Y. Liu, D.-L. Liao, S.-J. Tsai in Journal of Neural Transmission (2005)

Article

Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder

Serotonin systems appear to play a key role in the pathogenesis of major depression and the therapeutic mechanisms of antidepressants. The firing rate of dorsal raphe serotonergic neurons is controlled by soma...

C-J Hong, T-J Chen, Y W-Y Yu, S-J Tsai in The Pharmacogenomics Journal (2006)

Article

Lack of association of catechol-O-methyltransferase gene Val108/158Met polymorphism with schizophrenia: a family-based association study in a Chinese population

S-J Tsai, C-J Hong, S-J Hou, F-C Yen in Molecular Psychiatry (2006)

Article

Association study of polymorphisms in glycine transporter with schizophrenia

Glycine acts as an obligatory co-agonist with glutamate on N-methyl-D-aspartate (NMDA) receptors. Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake...

S.-J. Tsai, C.-Y. Cheng, C.-J. Hong, D.-L. Liao… in Journal of Neural Transmission (2006)

Article

Association study of polymorphisms in post-synaptic density protein 95 (PSD-95) with schizophrenia

The postsynaptic density protein 95 (PSD-95) – the prototype of this family – is a modular protein that enables anchoring of NMDA receptors, modulates NMDA receptor sensitivity to glutamate and coordinates NMD...

S.-J. Tsai, C.-J. Hong, C.-Y. Cheng, D.-L. Liao… in Journal of Neural Transmission (2007)

Article

Glycogen synthase kinase-3β gene is associated with antidepressant treatment response in Chinese major depressive disorder

Evidence suggests that glycogen synthase kinase-3β (GSK3B) activity is increased significantly in the brain of patients with major depressive disorders (MDD). Inhibition of GSK3B is thought to be a key feature...

S-J Tsai, Y-J Liou, C-J Hong, Y W-Y Yu, T-J Chen in The Pharmacogenomics Journal (2008)

Article

Gene–gene interactions of the INSIG1 and INSIG2 in metabolic syndrome in schizophrenic patients treated with atypical antipsychotics

The use of atypical antipsychotics (AAPs) is associated with increasing the risk of the metabolic syndrome (MetS), which is an important risk factor for cardiovascular disease and diabetes. Two insulin-induced...

Y-J Liou, Y M Bai, E Lin, J-Y Chen, T-T Chen, C-J Hong… in The Pharmacogenomics Journal (2012)

Article

Targeting TYRO3 inhibits epithelial–mesenchymal transition and increases drug sensitivity in colon cancer

Colon cancer is the third leading cause of death from cancer worldwide with less than 10% survival rate at the late stage. Although mutations of certain genes have been implicated in familial colon cancer deve...

C-W Chien, P-C Hou, H-C Wu, Y-L Chang, S-C Lin, S-C Lin, B-W Lin, J-C Lee… in Oncogene (2016)

Article

The difficulties in establishing an occupational exposure limit for carbon nanotubes

Concern over the health effects from the inhalation of carbon nanotubes (CNTs) has been building for some time, and adverse health effects found in animal studies include acute and chronic respiratory damage, ...

M. Ellenbecker, S-J. Tsai, M. Jacobs, M. Riediker… in Journal of Nanoparticle Research (2018)

Article

Co-aggregation of major psychiatric disorders in individuals with first-degree relatives with schizophrenia: a nationwide population-based study

A previous genetic study has suggested that schizophrenia, bipolar disorder, major depressive disorder, autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) share common disease-a...

C-M Cheng, W-H Chang, M-H Chen, C-F Tsai, T-P Su, C-T Li, S-J Tsai… in Molecular Psychiatry (2018)