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  1. Article

    Open Access

    Erratum: The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response

    Correction to: Translational Psychiatry (2015) 5, e553; doi:10.1038/tp.2015.47; published online 21 April 2015 Following publication, the authors identified an error in the meta-analysis of ISPC, AMPS and STAR...

    J M Biernacka, K Sangkuhl, G Jenkins, R M Whaley, P Barman… in Translational Psychiatry (2016)

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  2. Article

    Open Access

    ESICM LIVES 2016: part one

    L. Bos, L. Schouten, L. van Vught, M. Wiewel… in Intensive Care Medicine Experimental (2016)

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  3. Article

    Open Access

    The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response

    Response to treatment with selective serotonin reuptake inhibitors (SSRIs) varies considerably between patients. The International SSRI Pharmacogenomics Consortium (ISPC) was formed with the primary goal of id...

    J M Biernacka, K Sangkuhl, G Jenkins, R M Whaley, P Barman… in Translational Psychiatry (2015)

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  4. No Access

    Article

    Gene–gene interactions of the INSIG1 and INSIG2 in metabolic syndrome in schizophrenic patients treated with atypical antipsychotics

    The use of atypical antipsychotics (AAPs) is associated with increasing the risk of the metabolic syndrome (MetS), which is an important risk factor for cardiovascular disease and diabetes. Two insulin-induced...

    Y-J Liou, Y M Bai, E Lin, J-Y Chen, T-T Chen, C-J Hong… in The Pharmacogenomics Journal (2012)

  5. No Access

    Article

    Glycogen synthase kinase-3β gene is associated with antidepressant treatment response in Chinese major depressive disorder

    Evidence suggests that glycogen synthase kinase-3β (GSK3B) activity is increased significantly in the brain of patients with major depressive disorders (MDD). Inhibition of GSK3B is thought to be a key feature...

    S-J Tsai, Y-J Liou, C-J Hong, Y W-Y Yu, T-J Chen in The Pharmacogenomics Journal (2008)

  6. No Access

    Article

    Glucose–insulin homeostasis, lipid profiles and GH-IGF-IGFBP axis in clozapine-treated schizophrenic obesity versus non-psychiatric obesity

    Obese patients with schizophrenia being treated with clozapine and non-psychiatric obese are often assumed to share the same physiological changes in obesity. The aim of this study was to identify possible met...

    M-K Wu, C-Y Huang, Y J Liou, C-K Wang, S-D Lee in International Journal of Obesity (2008)

  7. No Access

    Article

    Association study of polymorphisms in post-synaptic density protein 95 (PSD-95) with schizophrenia

    The postsynaptic density protein 95 (PSD-95) – the prototype of this family – is a modular protein that enables anchoring of NMDA receptors, modulates NMDA receptor sensitivity to glutamate and coordinates NMD...

    S.-J. Tsai, C.-J. Hong, C.-Y. Cheng, D.-L. Liao… in Journal of Neural Transmission (2007)

  8. No Access

    Article

    Association study of polymorphisms in glycine transporter with schizophrenia

    Glycine acts as an obligatory co-agonist with glutamate on N-methyl-D-aspartate (NMDA) receptors. Brain glycine availability is determined by glycine transporters (GlyT1 or SLC6A9), which mediate glycine reuptake...

    S.-J. Tsai, C.-Y. Cheng, C.-J. Hong, D.-L. Liao… in Journal of Neural Transmission (2006)

  9. No Access

    Article

    Polymorphism of the adrenergic receptor alpha 2a −1291C>G genetic variation and clozapine-induced weight gain

    Weight gain, leading to further morbidity and poor treatment compliance, is a common consequence of treatment with clozapine. The substantial interindividual and interracial differences in drug-induced weight ...

    Y.-C. Wang, Y.-M. Bai, J.-Y. Chen, C.-C. Lin, I.-C. Lai… in Journal of Neural Transmission (2005)

  10. No Access

    Article

    Negative association between Catechol-O-methyltransferase (COMT) gene Val158Met polymorphism and persistent tardive dyskinesia in schizophrenia

    Chronic administration of typical antipsychotic agents, which mainly act on the dopamine receptors, implicates a role of dopamine system on the susceptibility of tardive dyskinesia (TD). In the present study, ...

    I.-C. Lai, Y.-C. Wang, C.-C. Lin, Y.-M. Bai, D.-L. Liao… in Journal of Neural Transmission (2005)

  11. No Access

    Article

    Association analysis of a neural nitric oxide synthase gene polymorphism and antipsychotics-induced tardive dyskinesia in Chinese schizophrenic patients

    Recent findings from rodent studies with chronic administration of antipsychotic drugs have indicated the role of neural nitric oxide synthase (NOS1) on the susceptibility of tardive dyskinesia (TD). In the pr...

    Y.-C. Wang, Y.-J. Liou, D.-L. Liao, Y.-M. Bai, C.-C. Lin… in Journal of Neural Transmission (2004)